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en:studie [2013/01/08 18:26]
80.86.255.130
en:studie [2013/03/27 13:01] (current)
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 Walach H, Möllinger H, Sherr J, Schneider R. "​Homeopathic pathogenetic trials produce more specific than non-specific symptoms: results from two double-blind placebo controlled trials."​ J Psychopharmacol. 2008 Jul;​22(5):​543-52. -- [[http://​www.ncbi.nlm.nih.gov/​pubmed/​18701641|http://​www.ncbi.nlm.nih.gov/​pubmed/​18701641]] Walach H, Möllinger H, Sherr J, Schneider R. "​Homeopathic pathogenetic trials produce more specific than non-specific symptoms: results from two double-blind placebo controlled trials."​ J Psychopharmacol. 2008 Jul;​22(5):​543-52. -- [[http://​www.ncbi.nlm.nih.gov/​pubmed/​18701641|http://​www.ncbi.nlm.nih.gov/​pubmed/​18701641]]
 +
 +Bracho G et al. 2010 - "​Large-scale application of highly-diluted bacteria for Leptospirosis epidemic ​
 +control."​ Homeopathy. 2010 Jul;​99(3):​156-66. [[http://​www.ncbi.nlm.nih.gov/​pubmed/​20674839]]
 +
  
 ==== Complex meta-analysis ==== ==== Complex meta-analysis ====
 +
 +Mathie RT et al. (2013) --//list of randomised controlled trials of homeopathy in humans, until 2011, 263 studies//-- "​Randomised controlled trials of homeopathy in humans: characterising the research journal literature for systematic review."​ Homeopathy. 2013 Jan;​102(1):​3-24.([[http://​www.ncbi.nlm.nih.gov/​pubmed/​23290875]])
  
 Bornhöft G. et al. "​Effectiveness,​ safety and cost-effectiveness of homeopathy in general practice -- summarized health technology assessment."​ Forsch Komplementmed. 2006;13 Suppl 2:19-29. Epub 2006 Jun 26. -- [[http://​www.ncbi.nlm.nih.gov/​pubmed/​16883077|http://​www.ncbi.nlm.nih.gov/​pubmed/​16883077]] Bornhöft G. et al. "​Effectiveness,​ safety and cost-effectiveness of homeopathy in general practice -- summarized health technology assessment."​ Forsch Komplementmed. 2006;13 Suppl 2:19-29. Epub 2006 Jun 26. -- [[http://​www.ncbi.nlm.nih.gov/​pubmed/​16883077|http://​www.ncbi.nlm.nih.gov/​pubmed/​16883077]]
 +
 +
 +//​__comments on Bornhöft study:​__// ​
 +    ​
 +//Shaw DM. The Swiss report on homeopathy: a case study of research misconduct. Swiss Med Wkly. 2012 May 31;​142:​w13594. [[http://​www.smw.ch/​content/​smw-2012-13594/​]] //
 +
 +//Reply to Shaw DM: von Ammon K, Bornhöft G, Maxion-Bergemann S, Righetti M, Baumgartner S,​Thurneysen A, Wolf U, Matthiessen PF. Familiarity,​ objectivity - and misconduct: Counterstatement to Shaw DM. The Swiss Report on homoeopathy:​ a case study of research misconduct. Swiss Med Wkly. 2012;​142:​w13594. [[http://​www.smw.ch/​content/​smw-2013-13720/​]] //
 +
 +**Meta-analysis of financial costs**
 +
 +Viksveen P, Dymitr Z, Simoens S. Economic evaluations of homeopathy: a review. Eur J Health Econ. 2013 Feb 10.([[http://​www.ncbi.nlm.nih.gov/​pubmed/​23397477]])
 +
  
 ==== Effects of highly-diluted substances on animals ==== ==== Effects of highly-diluted substances on animals ====
   * __**Database of studies:​**__ HomVetCR Database -- Veterinary Clinical Research-Database in Homeopathy -- //includes about 300 studies// -- [[http://​www.carstens-stiftung.de/​clinresvet/​index.php]]   * __**Database of studies:​**__ HomVetCR Database -- Veterinary Clinical Research-Database in Homeopathy -- //includes about 300 studies// -- [[http://​www.carstens-stiftung.de/​clinresvet/​index.php]]
 +
 +Clausen J et al. -- //review study, 48 studies from 1832-2009// -- "​Infection models in basic research on homeopathy"​. Homeopathy. 2010 Oct;​99(4):​263-70. ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​20970096]])
  
 Endler et al. "​Treatment of lowland frogs from the spawn stage with homeopathically prepared thyroxin (10(-30))."​ ScientificWorldJournal. 2007 Oct 22;​7:​1697-702. -- [[http://​www.ncbi.nlm.nih.gov/​pubmed/​17982565|http://​www.ncbi.nlm.nih.gov/​pubmed/​17982565]] Endler et al. "​Treatment of lowland frogs from the spawn stage with homeopathically prepared thyroxin (10(-30))."​ ScientificWorldJournal. 2007 Oct 22;​7:​1697-702. -- [[http://​www.ncbi.nlm.nih.gov/​pubmed/​17982565|http://​www.ncbi.nlm.nih.gov/​pubmed/​17982565]]
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 Endler et al. (2010) -- //review, repeated experiments in basic research, 107 studies, 24 models// -- "​Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study."​ Homeopathy. 2010 Jan;​99(1):​25-36.([[http://​www.ncbi.nlm.nih.gov/​pubmed/​20129174]]) Endler et al. (2010) -- //review, repeated experiments in basic research, 107 studies, 24 models// -- "​Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study."​ Homeopathy. 2010 Jan;​99(1):​25-36.([[http://​www.ncbi.nlm.nih.gov/​pubmed/​20129174]])
 +
 +  * **Animal studies**
 +
 +//​assumptions for study selection://​
 +
 +//- use of high potencies (12CH and more)//
 +
 +//- blinded conditions//​
 +
 +
 +//__effects on physiological functions:​__//​
 +
 +Ruiz-Vega et al. (2005)-- "​Histamine at high dilution reduces spectral density in delta band in sleeping rats". Homeopathy (2005), Vol. 94(2), pp. 86-91 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​15892488]])
 +
 +Welles et al. (2007)-- "​Pretreatment with thyroxin 10(-8) and the effect of homeopathically prepared thyroxin 10(-30) on highland frogs--a multi-researcher study."​ Forsch Komplementärmed (2007), Vol. 14(6), pp. 353-357 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​18219210]])
 +
 +Weber et al. (2008)-- "The effect of homeopathically prepared thyroxine on highland frogs: influence of electromagnetic fields"​. Homeopathy (2008), Vol. 97(1), pp. 3-9 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​18194759]])
 +
 +de Oliviera et al. (2011)--"​Mercurius solubilis: actions on macrophages"​. Homeopathy (2011), Vol. 100(4), pp. 228-236 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​21962197]])
 +
 +Kiefer et al. (2012) --"​Lowland amphibians - recalculation of data on effects of diluted thyroxine"​.
 +Int J High Dil Res (2012), Vol. 11(38), pp. 3-18 ([[http://​www.feg.unesp.br/​~ojs/​index.php/​ijhdr/​article/​view/​526]])
 +
 +//Negative findings://
 +
 +Velkers et al. (2005)-- "​Isopathic and pluralist homeopathic treatment of commercial broilers with experimentally induced colibacillosis"​ Res Vet Science (2005), Vol. 78(1), pp. 77-83([[http://​www.ncbi.nlm.nih.gov/​pubmed/​15500843]])
 +
 +Siegling-Vlitakis et al. (2009)-- "In vitro examination of potentized atropine sulfate dilutions on the contractility of the isolated rat ileum"​. J Altern Complement Med (2009), Vol. 15(10), pp. 1121-1126([[http://​www.ncbi.nlm.nih.gov/​pubmed/​19824820]])
 +
 +//__effects on animal emotions:​__//​
 +
 +Magnani et al. (2010) --"​Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice". Psychopharmacology (2010), Vol. 210(4), pp. 533-545 ([[http://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC2877813/​]])
 +
 +Bellavite et al. (2011)-- "​Effects of high-dilutions in behavioural models: a commentary on critical issues, from reproducibility to plausibility"​. Int J High Dilution Res 2011; 10(37): 325-337 ([[http://​www.feg.unesp.br/​~ojs/​index.php/​ijhdr/​article/​viewFile/​532/​550]])
 +
 +Bellavite et al. (2012) --"​Testing homeopathy in mouse emotional response models: pooled data analysis of two series of studies"​. eCAM (2012), Vol. Article ID 954374, pp. 1-9 ([[http://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3324905/​]])
 +
 +Heine et al. (2012) --"​Assessment of homeopathic medicine Aconitum napellus in the treatment of anxiety in an animal model"​. Int J High Dilution Res 2012; 11(38):​33-42 ([[http://​www.feg.unesp.br/​~ojs/​index.php/​ijhdr/​article/​viewArticle/​547]])
 +
 +//__effects on animal diseases and toxicological studies:​__//​
 +
 +Clausen J et al. (2013) -- //review of placebo-controlled trials in veterinary homeopathy, from 1965- April 2012, 203 controlled, 146 randomised, 57 non-randomised,​ 97 placebo-controlled trials// -- "​Veterinary Clinical Research Database for Homeopathy: Placebo-controlled trials."​ Complement Ther Med. 2013 Apr;​21(2):​115-20. ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​23497815]])
 +
 +Clausen J et al. -- //review study, 48 studies from 1832-2009// -- "​Infection models in basic research on homeopathy"​. Homeopathy. 2010 Oct;​99(4):​263-70. ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​20970096]])
 +
 +//later or selected older studies://
 +
 +Biswas et al. (2005)--"​Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-Dimethylaminoazobenzene-induced hepatocarcinogenesis in mice". J Altern Complement Med (2005), Vol. 11(5), pp. 839-854 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​16296917]])
 +
 +Paula Coelho et al. (2006)-- "​Therapeutic and pathogenetic animal models for Dolichos pruriens"​. Homeopathy (2006), Vol. 95(3), pp. 136-143([[http://​www.ncbi.nlm.nih.gov/​pubmed/​16815516]])
 +
 +Jonas et al. (2006)-- "Can homeopathic treatment slow prostate cancer growth?"​ Integr Cancer Ther (2006), Vol. 5(4), pp. 343-349 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​17101763]])
 +
 +MacLaughlin et al. (2006)-- "​Effects of homeopathic preparations on human prostate cancer growth in cellular and animal models"​. Integr Cancer Ther (2006), Vol. 5(4), pp. 362-372 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​17101766]])
 +
 +Banerjee et al. (2007)-- "A potentized homeopathic drug, Arsenicum album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice". J Vet Med (A) (2007), Vol. 54(7), pp. 370-376([[http://​www.ncbi.nlm.nih.gov/​pubmed/​17718811]])
 +
 +Pathak et al. (2007)-- "​Supportive evidence for the anticancerous potential of alternative medicine against hepatocarcinogenesis in mice". Forsch Komplementärmed (2007), Vol. 14(3), pp. 148-156 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​17596695]])
 +
 +Bhattacharjee et al. (2009)-- "​Homeopathic drugs Natrum sulphuricum and Carcinosin prevent azo dye-induced hepatocarcinogenesis in mice". Indian J Biochem Biophys (2009), Vol. 46(4), pp. 307-318 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​19788063]])
 +
 +Bhattacharjee et al. (2009)-- "​Amelioration of carcinogen-induced toxicity in mice by administration of a potentized homeopathic drug, Natrum sulphuricum 200". eCAM (2009), Vol. 6(1), pp. 65-75 ([[http://​www.hindawi.com/​journals/​ecam/​2009/​521217/​abs/​]])
 +
 +Goncalves de Araujo et al. (2009)-- "​Effect of Mercurius solubilis on the bacteriological response in the alveolitis process in rats". Homeopathy (2009), Vol. 98(3), pp. 160-164 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​19647210]])
 +
 +Kuzeff et al. (2009)-- "​Isopathic versus enantiomeric inhibition of U-50488 HCl toxicity"​ Homeopathy (2009), Vol. 98(2), pp. 83-87 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​19358960]])
 +
 +Pathak et al. (2009)-- "​Combinational homeopathic therapy reduces genotoxicity and cytotoxicity in mice fed carcinogenesis"​. Clin Exp Hom (2009), Vol. 1(1), pp. (1-10) ([[http://​www.sukulhomeopathy.com/​newjournal/​khuda-buksh1.pdf]])
 +
 +Viriato et al. (2009)-- "Study of high dilution of copaiba oil on inflammatory process"​. Int J High Dil Res (2009), Vol. 8(26), pp. 9-14 ([[http://​www.feg.unesp.br/​~ojs/​index.php/​ijhdr/​article/​viewFile/​305/​380]])
 +
 +Banerjee et al. (2010)-- "​Chelidonium majus 30C and 200C in induced hepato-toxicity in rats". Homeopathy (2010), Vol. 99(3)([[http://​www.ncbi.nlm.nih.gov/​pubmed/​20674840]])
 +
 +Ghilosso-Bortolini et al. (2010)-- "​Putative protective effect of Cadmium chloride high diluted solution on LLC-PK1 cell intoxicated by high concentration of this same metal"​. Int J High Dil Res (2010), Vol. 9(30), pp. 16-29 ([[http://​www.feg.unesp.br/​~ojs/​index.php/​ijhdr/​article/​viewArticle/​381]])
 +
 +Banerjee et al. (2011)-- "​Evidences of protective potentials of microdoses of ultra-high diluted arsenic trioxide in mice receiving repeated injections of arsenic trioxide"​. eCAM (2011), Vol. 2011 ([[http://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3135423/​]])
 +
 +Patil et al. (2011)-- "​Modulation of arthritis in rats by Toxicodendron pubescens and its homeopathic dilutions"​. Homeopathy (2011), Vol. 100(3) ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​21784329]])
 +
 +Bhattacharjee,​ Khuda-Bukhsh (2012)-- "Two homeopathic remedies used intermittently provide additional protective effects against hepatotoxicity induced by carcinogens in mice" J Acupunct Meridian Stud (2012), Vol. 5(4), pp. 166-175 (http://​www.ncbi.nlm.nih.gov/​pubmed/​22898065)
 +
 +Mohammadi et al. (2012)-- "​Homeopathic treatment for peripheral nerve regeneration:​ an experimental study in a rat sciatic nerve transection model."​ Homeopathy (2012), Vol. 101(3), pp. 141-146 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​22818230]])
 +
 +Patel et al. (2012)-- "​Toxicodendron pubescens retains its anti-arthritic efficacy at 1M, 10M and CM homeopathic dilutions."​ Homeopathy (2012), Vol. 101(3), pp. 165-170 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​22818234]])
 +
 +//Negative findings://
 +
 +Almeida et al. (2009)-- "​Homeopathic treatment for bone regeneration:​ experimental study."​ Homeopathy (2009), Apr;​98(2):​92-6. ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​19358962]])
 +
 +  * **Bacterial studies**
 +
 +Saha et al. (2012) -- "​Phenotypic evidence of ultra-highly diluted homeopathic remedies acting at gene expression level: a novel probe on experimental phage infectivity in bacteria"​ Journal of Chinese Integrative Medicine (2012), Vol. 10(4), pp. 462-470 ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​22500721]])
 +
 +Das S et al. (2012) -- "​Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes. Zhong Xi Yi Jie He Xue Bao. 2012 Mar;​10(3):​337-46. ([[http://​www.ncbi.nlm.nih.gov/​pubmed/​22409925]])
 +
 +De A et al. (2012) -- "​Potentized homeopathic drug Arsenicum album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenine-exposed bacteria Escherichia coli" J Chin Integr Med (2012), Vol. 10(2), pp. 210-227 ([[http://​www.jcimjournal.com/​en/​FullText2.aspx?​articleID=jcim20120212]])
  
   * **Studies on plants**   * **Studies on plants**
en/studie.1357669597.txt.gz · Last modified: 2013/01/08 18:26 by 80.86.255.130