Vedecké štúdie a homeopatia

Vedecké štúdie venujúce sa homeopatií sme rozdelili do štyroch častí:

• I. Databázy a zoznamy štúdií - v tejto časti sú odkazy na databázy a zoznamy homeopatických štúdií.

• II. Klinické štúdie klasickej homeopatie - časť venujúca sa výskumu klasickej (individualizovanej) homeopatie. V metodike týchto štúdii sú dodržané základné princípy homeopatie ako sú zákon podobnosti, podávanie minimálnej dávky a jedného lieku u každého pacienta (bližšie http://legatum.sk/sk:homeopathy). Predpis lieku je prísne individuálny. Autori stránky považujú výsledky práve týchto štúdií za najrelevantnejšie z pohľadu posúdenia účinnosti/neúčinnosti homeopatie.

• III. Ostatné klinické štúdie s použitím homeopatických liekov - v tejto časti sú zahrnuté klinické štúdie použitia homeopatických liekov spôsobmi, ktoré nespĺňajú základné princípy homeopatie (bližšie http://legatum.sk/sk:homeopathy). Predpis homeopatických liekov nie je výlučne individualizovaný. Z výsledkov týchto štúdii preto nie je možné urobiť záver o účinnosti/ neúčinnosti homeopatie. Väčšina mediálne diskusovaných štúdií homeopatie patrí práve do tejto oblasti.

• IV. Základný výskum v homeopatii - v tejto časti sme zaradili štúdie predklinického - základného výskumu homeopatie. Cieľom týchto štúdií je bližšie popísať a objasniť fenomény vznikajúce pri použití homeopatík (potencovaných látok) na živé a neživé systémy. Používajú sa tu rôzne fyzikálno-chemické, rastlinné a zvieracie modely.

I.1.Databázy štúdií:

• CORE-Hom Database - obsahuje vyše 1100 publikovaných štúdií u ľudí, štúdie sa dajú triediť podľa kritérii, stále dopĺňaná prehľadná databáza - http://archiv.carstens-stiftung.de/core-hom/login.php

• CAM-QUEST Database - obsahuje vyše 700 publikovaných štúdií u ľudí, obsahuje nielen homeopatické štúdie - http://www.cam-quest.org/en/search/therapies/?l1=403

• HomVetCR Database - Veterinary Clinical Research-Database in Homeopathy - obsahuje okolo 300 publikovaných štúdií na zvieratách - http://archiv.carstens-stiftung.de/clinresvet/index.php

• HomBRex database - The Homeopathic Basic Research experiments database - obsahuje viac než 1700 publikovaných experimentov základneho výskumu, 1300 článkov - http://archiv.carstens-stiftung.de/hombrex/index.php

I.2.Zoznamy randomizovaných štúdií:

• Mathie RT (2015) - prehľad štúdii – „Controlled clinical studies of homeopathy.“ Homeopathy. 2015 Oct;104(4):328-32.(http://www.ncbi.nlm.nih.gov/pubmed/26678738)

• Mathie RT et al. (2014) - štúdie 2012-2013 – 27 štúdií– „Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis.“ Syst Rev. 2014 Dec 6;3:142- Additional File 2.(http://www.systematicreviewsjournal.com/content/3/1/142)

• Mathie RT et al. (2013) - štúdie do roku 2011 – 263 štúdií, porovnanie s dvoma predchádzajúcimi prehľadmi (Linde et al., 1997; Shang et al., 2005)– „Randomised controlled trials of homeopathy in humans: characterising the research journal literature for systematic review.“ Homeopathy. 2013 Jan;102(1):3-24.(http://www.ncbi.nlm.nih.gov/pubmed/23290875)

• Clausen J et al. (2013) – prehľad klinických, placebom-kontrolovaných štúdií veterinárnej homeopatie, do apr/2012, 203 kontrolovaných, 146 randomizovaných, 57 nerandomizovaných, 97 placebom-kontrolovaných štúdií – „Veterinary Clinical Research Database for Homeopathy: Placebo-controlled trials.“ Complement Ther Med. 2013 Apr;21(2):115-20. (http://www.ncbi.nlm.nih.gov/pubmed/23497815)

• Mathie et al. (2012) –zoznam randomizovaných štúdií v homeopatií u zvierat, do marca 2011, 38 štúdií– „Randomised controlled trials of veterinary homeopathy: characterising the peer-reviewed research literature for systematic review“. Homeopathy. 2012 Oct;101(4):196-203. (http://www.ncbi.nlm.nih.gov/pubmed/23089214)

• Endler et al. (2010) - prehľadová práca, opakované experimenty základného výskumu, 107 štúdií, 24 modelov - „Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study.“ Homeopathy. 2010 Jan;99(1):25-36.(http://www.ncbi.nlm.nih.gov/pubmed/20129174)

II.1.) Metaanalýzy

• Mathie RT et al. (2014) - do roku 2014 najväčšia analýza randomizovaných štúdií individualizovanej homeopatie (peer-reviewed). Záver: možný špecifický účinok homeopatie (POR 1,53-1,98; p<0,001); celkovo nižšia kvalita sledovaných štúdii; nepotvrdilo sa, že štúdie s nižšou kvalitou vykazujú väčší terapeutický účinok homeopatie oproti štúdiám vyššej kvality; potreba ďalších štúdií „Randomised placebo-controlled trials of individualised homeopathic treatment: systematic review and meta-analysis.“ Syst Rev. 2014 Dec 6;3:142.(http://www.systematicreviewsjournal.com/content/3/1/142)

• Nuhn et al. (2010) - –Vplyv placeba u randomizovaných placebom kontrolovaných štúdií v klasickej homeopatií nezdá sa byť väčší ako u konvenčných štúdií.– „Placebo effect sizes in homeopathic compared to conventional drugs - a systematic review of randomised controlled trials.“ Homeopathy. 2010 Jan;99(1):76-82. (http://www.ncbi.nlm.nih.gov/pubmed/20129180)

• Linde K, Melchart D (1998) - Záver: možný špecifický účinok homeopatie; celkovo nižšia kvalita sledovaných štúdii; potreba ďalších štúdií „Randomized controlled trials of individualized homeopathy: a state-of-the-art review.“ J Altern Complement Med. 1998 Winter;4(4):371-88.(http://www.ncbi.nlm.nih.gov/pubmed/9884175, http://homeopathie-wijtenburg.nl/wp-content/uploads/2014/10/5-Linde-review-individualized-hom-JACM-1998.pdf)

• Ernst, (1998) - –komparatívna štúdia-vybraných 6 homeopatických a alopatických štúdií, nedostatočne popísaná metodika výberu štúdií a hodnotenia ich kvality so záverom: Slabá kvalita štúdii. Homeopatia v 2 štúdiách účinnejšia, v 2 horšia a v 2 rovnako účinná ako alopatická liečba. Nie je možné urobiť záver. http://www.crd.york.ac.uk/crdweb/ShowRecord.asp?View=Full&ID=11999000356#.VVEFdNPtlBd

III.A.1.) Metaanalýza účinnosti homeopatie bez individualizovanej (klasickej) homeopatie

• Mathie et al (2017) – Záver: analýza 75 randomizovaných štúdii (pre 48 klinických stavov do konca roku 2014) neindividualizovanej homeopatie ukazuje signifikantný rozdiel účinnosti homeopatie oproti placebu. Avšak pri zhodnotení kvalitnejších štúdii nebol prítomný signifikantný rozdiel v efektivite oproti placebu. „Randomised, double-blind, placebo-controlled trials of non-individualised homeopathic treatment: systematic review and meta-analysis.“ (https://www.ncbi.nlm.nih.gov/pubmed/28340607)

III.A.2.) Globálne metaanalýzy homeopatie - novšie

• Stub et al (2016) – „Adverse effects of homeopathy, what do we know? A systematic review and meta-analysis of randomized controlled trials.“ Klinické zhoršenie pacientov (tzv.homeopatické zhoršenie) je bežne popisované v homeopatických štúdiách. Percento klinicky zhoršených pacientov pri homeopatickej liečbe sa nelíši od klinicky zhoršených pacientov pri placebe a konvenčnej liečbe. Prehľadová práca a metanalýza randomizovaných klinických štúdii 1995-2011. (https://www.ncbi.nlm.nih.gov/pubmed/27261996)

• Australian NHMRC statement (2015) (https://www.nhmrc.gov.au/health-topics/complementary-medicines/homeopathy-review)- Kritický komentár: https://www.hri-research.org/resources/homeopathy-the-debate/the-australian-report-on-homeopathy/australian-nhmrc-report-in-detail/, http://www.homeopathyoz.org/news-8.html

• Bornhöft G. et al. (2011) – „Homeopathy in Healthcare – Effectiveness, Appropriateness, Safety, Costs - An HTA report on homeopathy as part of the Swiss Complementary Medicine Evaluation Programme.“(http://link.springer.com/book/10.1007/978-3-642-20638-2/page/1)

• Bornhöft G. et al. (2006) – „Effectiveness, safety and cost-effectiveness of homeopathy in general practice - summarized health technology assessment.“ Forsch Komplementmed. 2006;13 Suppl 2:19-29. Epub 2006 Jun 26. - http://www.ncbi.nlm.nih.gov/pubmed/16883077. Komentáre k práci Bornhöfta a kol.: Shaw DM. The Swiss report on homeopathy: a case study of research misconduct. Swiss Med Wkly. 2012 May 31;142:w13594. http://www.smw.ch/content/smw-2012-13594/ Reply to Shaw DM: von Ammon K, Bornhöft G, Maxion-Bergemann S, Righetti M, Baumgartner S,Thurneysen A, Wolf U, Matthiessen PF. Familiarity, objectivity - and misconduct: Counterstatement to Shaw DM. The Swiss Report on homoeopathy: a case study of research misconduct. Swiss Med Wkly. 2012;142:w13594. http://www.smw.ch/content/smw-2013-13720/

• Shang A et al. (2005) – „Are the clinical effects of homoeopathy placebo effects? Comparative study of placebo-controlled trials of homoeopathy and allopathy“. Lancet. 2005 Aug 27-Sep 2;366(9487):726-32. http://www.ncbi.nlm.nih.gov/pubmed/16125589. Popis štúdie:- Na analýzu bolo vybraných 110 homeopatických štúdií a 110 zodpovedajúcich štúdií konvenčnej medicíny. Konečné závery vznikli porovnaním štúdií väčších s lepšou kvalitou (1.pilier výskumu homeopatie-viď úvod) – 8 homeopatických a 6 konvenčnej medicíny. Záver Shang et al.: Dôkaz špecifického pôsobenia homeopatie je slabý, kdežto existuje silný dôkaz špecifického pôsobenia konvenčnej medicíny. Komentáre k práci Shanga et al.: Aj v tejto práci sa neprihliada ku kvalite použitej homeopatie (viď úvod) - iba dve z 8 porovnávaných homeopatických štúdií (https://apgaylard.wordpress.com/2007/11/28/the-myth-of-the-secret-eight/) mali dostatočnú kvalitu a skúmali individualizovanú (klasickú) homeopatiu (konkrétne Walach et al. 1997, Jacobs et al. 2000). To je dôvod nízkej externej validity výsledkov.

III.A.3.) Globálne metaanalýzy homeopatie - staršie

• a.) s dôležitými námietkami, ale homeopatia sa skôr líši od placeba:
  • Jonas et al, 2003 - http://www.annals.org/content/138/5/393.long
  • Cucherat et al, 2000 - http://www.ncbi.nlm.nih.gov/pubmed/10853874
  • Linde et al, 1997 - http://www.ncbi.nlm.nih.gov/pubmed/9310601 - nadstavba štúdie: - Linde et al, 1999 - http://www.ncbi.nlm.nih.gov/pubmed/10391656 - komentované: Ernst et al, 2000 - http://www.ncbi.nlm.nih.gov/pubmed/11186614 a Ludtke,2002 - http://www.ncbi.nlm.nih.gov/pubmed/11781130
  • Kleijnen et al, 1991 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1668980/

• b.) homeopatia sa nelíši od placeba
  • Ernst et al, 2002 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874503/

• c.) nezatriedené
  • Linde et al, 2001 - http://www.biomedcentral.com/1472-6882/1/4

III.A.4.) Vybrané užšie metaanalýzy (špecifické medicínske diagnózy, homeopatiká)

• Banerjee et al. (2017). „Homeopathy for Allergic Rhinitis: A Systematic Review.“ – Homeopatické randomizované štúdie pri alergickej rinitíde - nájdených celkovo 11 štúdií do decembra 2015 (izopatia, Galphimia glauca, nosný sprej). Záver: použitie Galphinie a homeopatického nosného spreja môže mať benefit na nosné a očné príznaky. Slabá kvalita štúdií. Doteraz neexistuje štúdia individualizovanej homeopatie u alergickej rinitídy. (https://www.ncbi.nlm.nih.gov/pubmed/28437146)

• Mathie RT, Frye J, Fisher P (2015). Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness. Cochrane Database Syst Rev. 2015 Jan 28;1:CD001957. (http://www.ncbi.nlm.nih.gov/pubmed/25629583)

III.B.1.) Metaanalýzy

• Mathie, Clausen (2015) –prvá globálna metaanalýza klinických randomizovaných štúdii veterinárnej homeopatie; zahŕňa 2 štúdie individualizovanej homeopatie, 10 štúdií neindividualizovanej homeopatie, 6 profylaktických štúdií - Záver: nízka kvalita štúdií, možný efekt homeopatickej liečby (OR=1,69-2,62, p=0,01-0,02). „Veterinary homeopathy: meta-analysis of randomised placebo-controlled trials.“ Homeopathy. 2015 Jan;104(1):3-8. http://www.ncbi.nlm.nih.gov/pubmed/25576265; Vet.Rec (2014) - http://www.ncbi.nlm.nih.gov/pubmed/25324413

III.B.2.) Vybrané klinické štúdie u zvierat

• Camerlink I. et al.(2010) „Homeopathy as replacement to antibiotics in the case of Escherichia coli diarrhoea in neonatal piglets.“ Homeopathy. 2010 Jan;99(1):57-62. - http://www.ncbi.nlm.nih.gov/pubmed/20129177

predpoklady vybratých štúdií: použitie vysokých potencií (12CH a viac) a zaslepené skúšanie

IV.A.1.) ovplyvnenie chorôb u ľudí:

• Teixeira MZ et al. – použitie potencovaného estrogénu pri zmiernení príznakov endometriózy. Príznaky endometriózy sú viazané na vyššie hladiny estrogénu. n=50 žien – „Potentized estrogen in homeopathic treatment of endometriosis-associated pelvic pain: A 24-week, randomized, double-blind, placebo-controlled study.“. Eur J Obstet Gynecol Reprod Biol. 2017 Jan 25;211:48-55. (https://www.ncbi.nlm.nih.gov/pubmed/28187404)

predpoklady vybratých štúdií: použitie vysokých potencií (12CH a viac) a zaslepené skúšanie

IV.B.1.) Ovplyvnenie fyziologických funkcií zvierat:

• Endler et al. (2007) „Treatment of lowland frogs from the spawn stage with homeopathically prepared thyroxin (10(-30)).“ ScientificWorldJournal. 2007 Oct 22;7:1697-702. - http://www.ncbi.nlm.nih.gov/pubmed/17982565

• Ruiz-Vega et al. (2005) – „Histamine at high dilution reduces spectral density in delta band in sleeping rats“. Homeopathy (2005), Vol. 94(2), pp. 86-91 (http://www.ncbi.nlm.nih.gov/pubmed/15892488)

• Welles et al. (2007) – „Pretreatment with thyroxin 10(-8) and the effect of homeopathically prepared thyroxin 10(-30) on highland frogs–a multi-researcher study.“ Forsch Komplementärmed (2007), Vol. 14(6), pp. 353-357 (http://www.ncbi.nlm.nih.gov/pubmed/18219210)

• Weber et al. (2008) – „The effect of homeopathically prepared thyroxine on highland frogs: influence of electromagnetic fields“. Homeopathy (2008), Vol. 97(1), pp. 3-9 (http://www.ncbi.nlm.nih.gov/pubmed/18194759)

• de Oliviera et al. (2011) –„Mercurius solubilis: actions on macrophages“. Homeopathy (2011), Vol. 100(4), pp. 228-236 (http://www.ncbi.nlm.nih.gov/pubmed/21962197)

• Kiefer et al. (2012) –„Lowland amphibians - recalculation of data on effects of diluted thyroxine“. Int J High Dil Res (2012), Vol. 11(38), pp. 3-18 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/526)

negatívny výsledok:

• Velkers et al. (2005) – „Isopathic and pluralist homeopathic treatment of commercial broilers with experimentally induced colibacillosis“ Res Vet Science (2005), Vol. 78(1), pp. 77-83(http://www.ncbi.nlm.nih.gov/pubmed/15500843)

• Siegling-Vlitakis et al. (2009) – „In vitro examination of potentized atropine sulfate dilutions on the contractility of the isolated rat ileum“. J Altern Complement Med (2009), Vol. 15(10), pp. 1121-1126(http://www.ncbi.nlm.nih.gov/pubmed/19824820)

IV.B.2.) ovplyvnenie chorôb a toxikologické štúdie u zvierat (okrem klinických štúdií s individualizovanou homeopatiou):

• Clausen J et al. – prehľadová práca, 48 štúdií z rokov 1832-2009 – „Infection models in basic research on homeopathy“. Homeopathy. 2010 Oct;99(4):263-70. (http://www.ncbi.nlm.nih.gov/pubmed/20970096)

novšie alebo vybrané staršie štúdie:

• Biswas et al. (2005) –„Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-Dimethylaminoazobenzene-induced hepatocarcinogenesis in mice“. J Altern Complement Med (2005), Vol. 11(5), pp. 839-854 (http://www.ncbi.nlm.nih.gov/pubmed/16296917)

• Paula Coelho et al. (2006) – „Therapeutic and pathogenetic animal models for Dolichos pruriens“. Homeopathy (2006), Vol. 95(3), pp. 136-143(http://www.ncbi.nlm.nih.gov/pubmed/16815516)

• Jonas et al. (2006) – „Can homeopathic treatment slow prostate cancer growth?“ Integr Cancer Ther (2006), Vol. 5(4), pp. 343-349 (http://www.ncbi.nlm.nih.gov/pubmed/17101763)

• MacLaughlin et al. (2006) – „Effects of homeopathic preparations on human prostate cancer growth in cellular and animal models“. Integr Cancer Ther (2006), Vol. 5(4), pp. 362-372 (http://www.ncbi.nlm.nih.gov/pubmed/17101766)

• Banerjee et al. (2007) – „A potentized homeopathic drug, Arsenicum album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice“. J Vet Med (A) (2007), Vol. 54(7), pp. 370-376(http://www.ncbi.nlm.nih.gov/pubmed/17718811)

• Pathak et al. (2007) – „Supportive evidence for the anticancerous potential of alternative medicine against hepatocarcinogenesis in mice“. Forsch Komplementärmed (2007), Vol. 14(3), pp. 148-156 (http://www.ncbi.nlm.nih.gov/pubmed/17596695)

• Bhattacharjee et al. (2009) – „Homeopathic drugs Natrum sulphuricum and Carcinosin prevent azo dye-induced hepatocarcinogenesis in mice“. Indian J Biochem Biophys (2009), Vol. 46(4), pp. 307-318 (http://www.ncbi.nlm.nih.gov/pubmed/19788063)

• Bhattacharjee et al. (2009) – „Amelioration of carcinogen-induced toxicity in mice by administration of a potentized homeopathic drug, Natrum sulphuricum 200“. eCAM (2009), Vol. 6(1), pp. 65-75 (http://www.hindawi.com/journals/ecam/2009/521217/abs/)

• Goncalves de Araujo et al. (2009) – „Effect of Mercurius solubilis on the bacteriological response in the alveolitis process in rats“. Homeopathy (2009), Vol. 98(3), pp. 160-164 (http://www.ncbi.nlm.nih.gov/pubmed/19647210)

• Kuzeff et al. (2009) – „Isopathic versus enantiomeric inhibition of U-50488 HCl toxicity“ Homeopathy (2009), Vol. 98(2), pp. 83-87 (http://www.ncbi.nlm.nih.gov/pubmed/19358960)

• Pathak et al. (2009) – „Combinational homeopathic therapy reduces genotoxicity and cytotoxicity in mice fed carcinogenesis“. Clin Exp Hom (2009), Vol. 1(1), pp. (1-10) (http://www.sukulhomeopathy.com/newjournal/khuda-buksh1.pdf)

• Viriato et al. (2009) – „Study of high dilution of copaiba oil on inflammatory process“. Int J High Dil Res (2009), Vol. 8(26), pp. 9-14 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/305/380)

• Banerjee et al. (2010) – „Chelidonium majus 30C and 200C in induced hepato-toxicity in rats“. Homeopathy (2010), Vol. 99(3)(http://www.ncbi.nlm.nih.gov/pubmed/20674840)

• Ghilosso-Bortolini et al. (2010) – „Putative protective effect of Cadmium chloride high diluted solution on LLC-PK1 cell intoxicated by high concentration of this same metal“. Int J High Dil Res (2010), Vol. 9(30), pp. 16-29 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/381)

• Magnani et al. (2010) –„Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice“. Psychopharmacology (2010), Vol. 210(4), pp. 533-545 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877813/)

• Banerjee et al. (2011) – „Evidences of protective potentials of microdoses of ultra-high diluted arsenic trioxide in mice receiving repeated injections of arsenic trioxide“. eCAM (2011), Vol. 2011 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135423/)

• Patil et al. (2011) – „Modulation of arthritis in rats by Toxicodendron pubescens and its homeopathic dilutions“. Homeopathy (2011), Vol. 100(3) (http://www.ncbi.nlm.nih.gov/pubmed/21784329)

• Bellavite et al. (2011) – „Effects of high-dilutions in behavioural models: a commentary on critical issues, from reproducibility to plausibility“. Int J High Dilution Res 2011; 10(37): 325-337 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/532/550)

• Bhattacharjee, Khuda-Bukhsh (2012) – „Two homeopathic remedies used intermittently provide additional protective effects against hepatotoxicity induced by carcinogens in mice“ J Acupunct Meridian Stud (2012), Vol. 5(4), pp. 166-175 (http://www.ncbi.nlm.nih.gov/pubmed/22898065)

• Mohammadi et al. (2012) – „Homeopathic treatment for peripheral nerve regeneration: an experimental study in a rat sciatic nerve transection model.“ Homeopathy (2012), Vol. 101(3), pp. 141-146 (http://www.ncbi.nlm.nih.gov/pubmed/22818230)

• Patel et al. (2012) – „Toxicodendron pubescens retains its anti-arthritic efficacy at 1M, 10M and CM homeopathic dilutions.“ Homeopathy (2012), Vol. 101(3), pp. 165-170 (http://www.ncbi.nlm.nih.gov/pubmed/22818234)

• Bellavite et al. (2012) –„Testing homeopathy in mouse emotional response models: pooled data analysis of two series of studies“. eCAM (2012), Vol. Article ID 954374, pp. 1-9 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324905/)

• Heine et al. (2012) –„Assessment of homeopathic medicine Aconitum napellus in the treatment of anxiety in an animal model“. Int J High Dilution Res 2012; 11(38):33-42 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/547)

negatívny výsledok:

• Almeida et al. (2009) – „Homeopathic treatment for bone regeneration: experimental study.“ Homeopathy (2009), Apr;98(2):92-6. (http://www.ncbi.nlm.nih.gov/pubmed/19358962)

IV.C.1.) ovplyvnenie fyziologických funkcií rastlín (rastu, zloženia,…):

• Majewsky et al. (2009) - prehľadová práca štúdií z rokov 1920-2009, 86 štúdií - „Use of homeopathic preparations in experimental studies with healthy plants.“ Homeopathy. 2009 Oct;98(4):228-43.(http://www.ncbi.nlm.nih.gov/pubmed/19945677)

novšie alebo vybrané staršie štúdie:

* IV.C.1.a) Ovplyvnenie rastu

* - potencované látky - viaceré

• Jäger et al. (2010) - (prednáška) „Comparative study of two bioassays with weakened duckweed and yeast treated with homeopathic preparations“ Int J High Dilution Res 2012; 11(40):129-130 (http://www.researchgate.net/publication/257874737_P01.52._Comparative_study_of_two_bioassays_with_stressed_duckweed_and_yeast_treated_with_homeopathic_preparations)

• Gangar (2010) - „Management of genetic activity through homoeopathy.“ Int J Pharma Bio Sci (2010), Vol. 1(2), pp. 1-13(http://www.ijpbs.net/issue-2/177.pdf)

• Scherr et al. (2009) - „Effects of potentised substances on growth rate of the water plant Lemna gibba L.“ Complement Ther Med. 2009 Apr;17(2):63-70.(http://www.ncbi.nlm.nih.gov/pubmed/19185263)

• Scherr C et al. (2007) - „Duckweed (Lemna gibba L.) as a test organism for homeopathic potencies.“ J Altern Complement Med. 2007 Nov;13(9):931-7.(http://www.ncbi.nlm.nih.gov/pubmed/18047439)

• Baumgartner et al. (2004) - „Growth Stimulation of Dwarf Peas (Pisum sativum L.) Through Homeopathic Potencies of Plant Growth Substances.“ Forsch Komplementärmed (2004), Vol. 11(5), pp. 281-292(http://www.ncbi.nlm.nih.gov/pubmed/15572869)

* - potencované giberelíny

• Majewsky et al. (2014). –„Reproducibility of effects of homeopathically potentised gibberellic acid on the growth of Lemna gibba L. in a randomised and blinded bioassay.“ Homeopathy. 2014 Apr;103(2):113-26. (http://www.ncbi.nlm.nih.gov/pubmed/24685416)

• Hribar-Marko et al. (2013). –„Prestimulation of wheat seedlings with gibberellic acid followed by application of an agitated high dilution of the same hormone“ Int J High Dilution Res (2013), Vol. 12(42), pp. 26-39 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/617)

• Hribar-Marko et al. (2012). –„Pre stimulation by gibberellic acid and the effect of extremely diluted agitated gibberellic acid on wheat stalk growth.“ Int J High Dilution Res 2012; 11: 124e125. (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/605)

• Kiefer ET AL. (2012) - „Wheat germination and highly diluted agitated gibberellic acid (10 -30) - a multi researcher study“. Int J High Dil Res (2012), Vol. 11(39), pp. 45-59(http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/428)

• Endler et al. (2011) - „Seasonal Variation of the Effect of Extremely Diluted Agitated Gibberellic Acid (10e-30) on Wheat Stalk Growth: A Multiresearcher Study“. TheSWJ Volume 11 (2011), Pages 1667-1678 (http://www.hindawi.com/journals/tswj/2011/462736/)

• Pfleger et al. (2011) - „The effect of extremely diluted agitated gibberellic acid (10e-30) on wheat stalk growth-A two researcher pilot study.“ Complement Ther Med. 2011 Jun;19(3):164-9. Epub 2011 May 20. - http://www.ncbi.nlm.nih.gov/pubmed/21641523

• Bonfim et al. (2008) - „Use of homeopathic Arnica montana for the issuance of roots of Rosmarinus officinalis L. and Lippia alba (Mill.) N.E.Br.“ Int J High Dil Res (2008), Vol. 7(23), pp. 72-76(http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/276)

* IV.C.1.b) Ovplyvnenie chemického zloženia

• Bonato et al. (2009) - „Homeopathic drugs Arsenicum album and Sulphur affect the growth and essential oil content in mint (Mentha arvensis L.)“ Acta Scientarum Agronomy (2009), Vol. 31(1), pp. 101-105(http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/6642)

* IV.C.1.c) Iné: -

IV.C.2.) ovplyvnenie rastlinných chorôb:

• Betti et al. (2009) - prehľad fytopatologických štúdii z rokov 1969-2009, 44 štúdií, rastlina + vírusy, huby, baktérie, nematody - „Use of homeopathic preparations in phytopathological models and in field trials: a critical review.“ Homeopathy. 2009 Oct;98(4):244-66.(http://www.ncbi.nlm.nih.gov/pubmed/19945678)

novšie alebo vybrané staršie štúdie:

• Datta, Datta (2012) - „Homeopathic medicines protect environment, health and development by controlling mulberry disease.“ J Homeopath Ayurv Med (2012), Vol. 1(1), pp. 1-7(http://www.omicsgroup.org/journals/2167-1206/2167-1206-1-104.php?aid=4121)

• Wyss et al. (2010) - „Homeopathic preparations to control the rosy apple aphid (Dysaphis plantaginea Pass.)“ Scientific World J (2010), Vol. 10, pp. 38-48(http://www.hindawi.com/journals/tswj/2010/358407/abs/)

• Shah-Rossi et al. (2009) - „Homeopathic treatment of Arabidopsis thaliana plants infected with Pseudomonas syringae.“ ScientificWorldJournal. 2009 May 20;9:320-30. (http://www.ncbi.nlm.nih.gov/pubmed/19468651)

• Datta (2006) - „Effects of Cina on root-knot disease of mulberry.“ Homeopathy. 2006 Apr;95(2):98-102.(http://www.ncbi.nlm.nih.gov/pubmed/16569626)

• Sukul et al. (2006) - „Amelioration of root-knot disease of lady's finger plants by potentized Cina and Santonin.“ Homeopathy. 2006 Jul;95(3):144-7.(http://www.ncbi.nlm.nih.gov/pubmed/16815517)

IV.C.3.) zvýšenie odolnosti rastlín voči vonkajším vplyvom

• Jäger et al. (2011) – prehľadová práca štúdií z rokov 1920-2010, 34 štúdií rôznej kvality - „Use of homeopathic preparations in experimental studies with abiotically stressed plants.“ Homeopathy. 2011 Oct;100(4):275-87.(http://www.ncbi.nlm.nih.gov/pubmed/21962204)

novšie alebo vybrané staršie štúdie:

• Betti et al. (2013) – „Extremely low doses of arsenic affect in vitro pollen germination.“ Forsch Komplementmed. 2013;20(4):254-60. (http://www.ncbi.nlm.nih.gov/pubmed/24030446)

• Jäger et al. (2012) – „Comparative study of two bioassays with weakened duckweed and yeast treated with homeopathic preparations.“ Int J High Dilution Res 2012; 11: 129e130. (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/574)

• Mondal et al. (2012) –„Natrum mur 200c promotes seed germination and increases total protein, chlorophyll, rubisco and sugar in early seedlings of cowpea under salt stress.“ Int JHigh Dilution Res 2012; 11: 128. (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/570)

• Brizzi et al. (2011) - „The efficacy of ultramolecular aqueous dilutions on a wheat germination model as a function of heat and aging-time“. eCAM (2011), Vol. 2011, pp. 696298; (1-11)(http://www.hindawi.com/journals/ecam/2011/696298/)

• Bonfim et al. (2010) - „ Germination and vigor of lettuce seeds (Lactuca sativa L.) pelleted with homeopathic preparations Alumina and Calcarea carbonica subjected to toxic levels of aluminum“. Int J High Dil Res (2010), Vol. 9(33), pp. 138-146 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/412/450)

• Jäger et al. (2010) - „Effects of homeopathic arsenicum album, nosode, and gibberellic acid preparations on the growth rate of arsenic-impaired duckweed (Lemna gibba L.)“ Scientific World J (2010), Vol. 10, pp. 2112-2129(http://www.hindawi.com/journals/tswj/2010/107597/abs/)

• Lahnstein et al. (2009) - „Isopathic treatment effects of Arsenicum album 45x on wheat seedling growth–further reproduction trials.“ Homeopathy (2009), Vol. 98(4)(http://www.ncbi.nlm.nih.gov/pubmed/19945675)

• Binder et al. (2005) - „The effects of a 45x potency of arsenicum album on wheat seedling growth – a reproduction trial.“ Forsch Komplementarmed Klass Naturheilkd. 2005 Oct;12(5):284-91.(http://www.ncbi.nlm.nih.gov/pubmed/16230858)

IV.C.4.) ďalšie špecifické výskumné modely

• Baumgartner et al. (2014) - „Spatial allocation effects within a potentization basic research model – evidence for field-like effects of homeopathic preparations? “ International Journal of High Dilution Research, Vol 13, No 47 (2014).(http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/748)

• Saha et al. (2012) – „Phenotypic evidence of ultra-highly diluted homeopathic remedies acting at gene expression level: a novel probe on experimental phage infectivity in bacteria“ Journal of Chinese Integrative Medicine (2012), Vol. 10(4), pp. 462-470 (http://www.ncbi.nlm.nih.gov/pubmed/22500721)

• Das S et al. (2012) – „Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes. Zhong Xi Yi Jie He Xue Bao. 2012 Mar;10(3):337-46. (http://www.ncbi.nlm.nih.gov/pubmed/22409925)

• De A et al. (2012) – „Potentized homeopathic drug Arsenicum album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenine-exposed bacteria Escherichia coli“ J Chin Integr Med (2012), Vol. 10(2), pp. 210-227 (http://www.jcimjournal.com/en/FullText2.aspx?articleID=jcim20120212)

• Witt et al., (2007) - sytematický prehľad, 67 experimentov z rokov 1966-2005, 1/3 replikovaný výskum- zahrnuté nebunkové systémy(väčšinou enzýmy), bunkové kultúry, bunky izolované z organizmov (erytrocyty, bazofily, neutrofily, lymfocyty) http://www.ncbi.nlm.nih.gov/pubmed/17544864

novšie alebo vybrané staršie štúdie:

• Malarczyk, E. (2008) - „Kinetic changes in activity of HR-peroxidase, induced by very low doses of phenol“. Int J High Dil Res (2008), Vol. 7(23), pp. 3-11 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/37/349)

efekt na zmenu expresie génov buniek:

• Olsen, S. (2017) - „Effects of ultra-high dilutions of sodium butyrate on viability and gene expression in HEK 293 cells.“. Homeopathy 2017 Feb;106(1):32-36 (https://www.ncbi.nlm.nih.gov/pubmed/28325222) - diskusia s ďalšími staršími štúdiami.

IV.F.1.) Termoluminiscencia

• Rey L. (2003) - „Thermoluminescence of ultra-high dilutions of lithium chloride and sodium chloride.“ Physica A (2003), Vol. 323, pp. 67-74. (http://dx.doi.org/10.1016/S0378-4371(03)00047-5)

• van Wijk R et al. (2006) - „Thermoluminescence in ultra-high dilution research.“ J Altern Complement Med. 2006 Jun;12(5):437-43.(http://www.ncbi.nlm.nih.gov/pubmed/16813507)

• Rey L. (2007) - „Can low-temperature thermoluminescence cast light on the nature of ultra-high dilutions?“ Homeopathy (2007), Vol. 96(3), pp. 170-174. (http://www.ncbi.nlm.nih.gov/pubmed/17678813)

IV.F.2.) Spektroskopia

• Klein SD., Wolf U. (2016). –„Comparison of homeopathic globules prepared from high and ultra-high dilutions of various starting materials by ultraviolet light spectroscopy“ / Complementary Therapies in Medicine 24 (2016) 111–117. (http://www.complementarytherapiesinmedicine.com/article/S0965-2299%2815%2930038-8/pdf)

• Sukul et al. (2005) - FTIR - „Variation in Fourier transform infrared spectra of some homeopathic potencies and their diluent media. J Altern Complement Med. 2005 Oct;11(5):807-12. (http://www.ncbi.nlm.nih.gov/pubmed/16296914)

• Rao et al. (2008) - UV spektroskopia, Ramanova spektroskopia - „Characterization of the structure of ultra dilute sols with remarkable biological properties“ Mater Lett. 2008 April 15; 62(10-11): 1487. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822343/)

• Bhattacharya et al. (2008) - rôzne spektroskopie, rozdiely v spektrách pri rôznych nádobách, potenciách, pri rôznych postupoch prípravy, in vitro ovplyvnenie rastu HeLa - „In vitro studies demonstrate anticancer activity of an alkaloid of the plant Gelsemium sempervirens“. Exp Biol Med (2008), Vol. 233(12), pp. 1591-1601. (http://www.ncbi.nlm.nih.gov/pubmed/18997108)

• Botha I, Ross AH. (2008) - MR spektrokopia - „A nuclear magnetic resonance spectroscopy comparison of 3C trituration derived and 4C trituration derived remedies“. Homeopathy. 2008 Oct;97(4):196-201. (http://www.ncbi.nlm.nih.gov/pubmed/19371568)

• de Alvarenga et al. (2009) - 13C MR spektroskopia - „Effect of Magnesium phosphoricum 12c on Sodium Dodecylsulphate by 13C nuclear magnetic resonance“. Int J High Dil Res (2009), Vol. 8(26), pp. 3-8 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/324/379)

• Sharma A., Purkait B. (2009) - UV spektroskopia - „Energy in Commercially Available Ultra-Diluted Natural Cardiotropic Drug Digitalis purpurea: An UV Spectroscopic Study. Research Journal of Pharmacology, 3: 58-62. (http://medwelljournals.com/abstract/?doi=rjpharm.2009.58.62)

• Sharma A. et al. (2010) - FTIR, Ramanova spektroskopia - „Identification of medicinally active ingredients in ultradiluted Digitalis purpurea. FTIR and Raman spectroscopic studies.“ Medicinal Chemistry Research, vol. 19, no. 7, pp. 643–651, 2010.(http://dx.doi.org/10.1007/s00044-009-9219-3)

• Marschollek et al. (2010) - UV spektroskopia, skúmanie vonkajších vplyvov na homeopatiká - „Effects of exposure to physical factors on homeopathic preparations as determined by ultraviolet light spectroscopy“. Scientific World J (2010), Vol. 10, pp. 49-81 (http://www.ncbi.nlm.nih.gov/pubmed/20062950)

• Wolf et al. (2011) - UV spektroskopia - „Homeopathic Preparations of Quartz, Sulfur and Copper Sulfate Assessed by UV-Spectroscopy.“ Evid Based Complement Alternat Med. 2011;2011:692798. (http://www.ncbi.nlm.nih.gov/pubmed/19474239)

• Sharma A., Purkait B. (2012) - Florescenčná spektroskopia, cyklická voltametria- „Identification of Medicinally Active Ingredient in Ultradiluted Digitalis purpurea: Fluorescence Spectroscopic and Cyclic-Voltammetric Study.“ Journal of Analytical Methods in Chemistry, vol. 2012, Article ID 109058, 5 pages, 2012. (http://dx.doi.org/10.1155/2012/109058)

• Klein et al. (2012) – UV spektroskopia - „Investigating homeo- pathic preparations with light spectroscopy.“ Int J High Dilution Res 2012; 11: 117.(http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/584)

Negatívne nálezy:

• Aabel et al. (2001) - 1H MR Spektroskopia, T1 relaxačné časy- „Nuclear magnetic resonance (NMR) studies of homeopathic solutions.“ Br Homeopath J. 2001 Jan;90(1):14-20. (http://www.ncbi.nlm.nih.gov/pubmed/11212083)

• Anick DJ. (2004) - 1H MR Spektroskopia- „High sensitivity 1H-NMR spectroscopy of homeopathic remedies made in water.“ BMC Complement Altern Med. 2004 Nov 1;4:15. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534805/)

IV.F.3.) Elektrónová mikroskopia

dôkaz nanočastíc pôvodnej látky aj pri extrémnych zriedeniach

• Chikramane et al. (2010) - „Extreme homeopathic dilutions retain starting materials: A nanoparticulate perspective“. Homeopathy (2010), Vol. 99(4), pp. 231-242. (http://www.ncbi.nlm.nih.gov/pubmed/20970092)

• Chikramane et al. (2012) - „Why extreme dilutions reach non-zero asymptotes: a nanoparticulate hypothesis based on froth flotation.“ Langmuir. 2012 Nov 13;28(45):15864-75. (http://www.ncbi.nlm.nih.gov/pubmed/23083226)

IV.F.4.) Magnetická rezonancia

Homeopatické preparáty vo vysokých riedeniach vykazujú oproti kontrolným roztokom zmeny relaxačných časov.

• Demangeat et al. (2004) - „Low-field NMR water proton longitudinal relaxation in ultrahighly diluted aqueous solutions of silica-lactose prepared in glass material for pharmaceutical use“. Appl Magn Reson (2004), Vol. 26, pp. 465-481 (http://link.springer.com/article/10.1007%2FBF03166577)

• Demangeat J-L. (2009) - „NMR water proton relaxation in unheated and heated ultrahigh aqueous dilutions of histamine: Evidence for an air-dependent supramolecular organization of water.“ Journal of Molecular Liquids, 144:32-39 (http://www.homeopathyeurope.org/media/news/Demangeat_JML_2009.pdf/view)

• Baumgartner S. et al. (2009) - „High-field 1H T1 and T2 NMR relaxation time measurements of H2O in homeopathic preparations of quartz, sulfur, and copper sulfate.“ Naturwissenschaften, vol. 96, pp. 1079–1089, 2009. (http://www.springerlink.com/content/044012g3574214m1/)

• Demangeat, J.L. (2010) - „NMR relaxation evidence for solute-induced nanosized superstructures in ultramolecular aqueous dilutions of silica-lactose“ J Molecular Liquids (2010), Vol. 155 (http://dx.doi.org/10.1016/j.molliq.2010.05.010)

• Demangeat (2013) – „Nanosized solvent superstructures in ultramolecular aqueous dilutions: twenty years' research using water proton NMR relaxation.““ Homeopathy. 2013 Apr;102(2):87-105. (http://www.ncbi.nlm.nih.gov/pubmed/23622259)

Negatívne nálezy:

• Aabel et al. (2001) - T1 relaxačné časy, 1H MR Spektroskopia- „Nuclear magnetic resonance (NMR) studies of homeopathic solutions.“ Br Homeopath J. 2001 Jan;90(1):14-20. (http://www.ncbi.nlm.nih.gov/pubmed/11212083)

• Milgrom et al. (2001) - T2 relaxačné časy - nie je rozdiel v relaxačných časoch medzi zriedenou a potencovanou substanciou- „On the investigation of homeopathic potencies using low resolution NMR T2 relaxation times.“ Brit Hom J (2001), Vol. 90(1), pp. 5-13 (http://www.ncbi.nlm.nih.gov/pubmed/11212090)

IV.F.5.) Kalorimetria, elektrická vodivosť, potenciometria

Vysokozriedené (a potencované) substancie za Avogadrov limit sa líšia svojimi fyzikálno-chemickými vlastnosťami oproti samotnému rozpúšťadlu.

• Elia V, Niccoli M (1999) - „Thermodynamics of extremely diluted aqueous solutions.“ Annals of the New York Academy of Sciences, 879:241–248 (http://www.ncbi.nlm.nih.gov/pubmed/10415834)

• Petrov SI, Epstein OI. (2003) - „Effect of potentiated solutions on mercury(II) signal in inversion voltammetry.“ Bull Exp Biol Med. 2003 Jan;135 Suppl 7:99-101. (http://dx.doi.org/10.1023/A%3A1024707519510)

• Elia V, Niccoli M (2004) - „New physico-chemical properties of extremely diluted aqueous solutions.“ Journal of Thermal Analysis and Calorimetry, 75: 815–836 (http://dx.doi.org/10.1023/B:JTAN.0000042179.07858.c8)

• Elia et al. (2004) - „Permanent physico-chemical properties of extremely diluted aqueous solutions of homeopathic medicines.“ Homeopathy, Volume 93, Issue 3, Pages 144-150. (http://dx.doi.org/10.1016/j.homp.2004.04.004)

• Elia et al. (2004) - „New physico-chemical properties of extremely diluted aqueous solutions: A calorimetric and conductivity study at 25°C.“ Journal of Thermal Analysis and Calorimetry, 78: 331–342.

• Elia et al. (2005) - „Hydrohysteretic phenomena of “extremely diluted solutions” induced by mechanical treatments. A calorimetric and conductometric study at 25 °C.“ Journal of Solution Chemistry, 34:947–960 (http://dx.doi.org/10.1007/s10953-005-6258-3)

• Elia et al. (2006) - „Extremely diluted solutions as multi-variable systems. A study of calorimetric and conductometric behaviour as function of the parameter time.“ Journal of Thermal Analysis and Calorimetry, 84:317–323 (http://dx.doi.org/10.1007/s10973-005-7266-7)

• Elia et al. (2008) - „New Physico-Chemical Properties of Extremely Dilute Solutions. A Conductivity Study at 25 °C in Relation to Ageing.“ Journal of Solution Chemistry, 37:85-96 (http://dx.doi.org/10.1007/s10953-007-9215-5)

• Elia et al. (2008) - „On the stability of extremely diluted aqueous solutions at high ionic strength - A calorimetric study at 298 K.“ Journal of Thermal Analysis and Calorimetry, 92:643-648 (http://dx.doi.org/10.1007/s10973-007-8840-y)

• Belon et al. (2008) - „Conductometric and calorimetric studies of the serially diluted and agitated solutions. On the combined anomalous effect of time and volume parameters.“ Journal of Thermal Analysis and Calorimetry, 93, 459-469 (http://dx.doi.org/10.1007/s10973-007-8580-z)

• Elia et al. (2008) - „Physico-chemical properties of aqueous extremely diluted solutions in relation to ageing.“ Journal of Thermal Analysis and Calorimetry, 93:1003-1011 (http://dx.doi.org/10.1007/s10973-007-8843-8)

• Holandino et al. (2008) - „Modeling physical-chemical properties of high dilutions“. Int J High Dil Res (2008), Vol. 7(25), pp. 165-173 (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/319/375)

• Elia et al. (2010) - „Thermodynamic parameters for the binding process of the OH− ion with the dissipative structures. Calorimetric and conductometric titrations.“ Journal of Thermal Analysis and Calorimetry, Online First™, 11 April 2010 (http://dx.doi.org/10.1007/s10973-010-0757-1)

• Garcia et al. (2010) - „Physical chemical and citotoxic evaluation of highly diluted solutions of Euphorbia tirucalli L. prepared through the fifty milesimal homeopathic method“. Int J High Dil Res (2010), Vol. 9(31) (http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/383/439)

IV.F.6.) Biokryštalizácia

• Kokornaczyk et al. (2014) - „Droplet evaporation method as a new potential approach for highlighting the effectiveness of ultra high dilutions.“ Complement Ther Med. 2014 Apr;22(2):333-40.(http://www.ncbi.nlm.nih.gov/pubmed/24731905)

• Baumgartner S. et al. (2012) - „Development of a Biocrystallisation Assay for Examining Effects of Homeopathic Preparations Using Cress Seedlings.“ Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 125945, 14 pages, 2012. (http://dx.doi.org/10.1155/2012/125945)

IV.F.7.) Kirlianov efekt

• Bell et al. (2003) - „Gas discharge visualisation evaluation of ultramolecular doses of homeopathic medicines under blinded, controlled conditions.“ Journal of Alternative and Complementary Medicine, 9:25–38. (http://www.ncbi.nlm.nih.gov/pubmed/12676033)

• Peters et al. (2009) - „Biophoton emission in high-potency research on wheat seed models“. Eur J Integr Med (2009), Vol. 1(4) (http://www.sciencedirect.com/science/article/pii/S1876382009001711#)

• Assumpcao, R. (2008) - „Electrical impedance and HV plasma images of high dilutions of sodium chloride“. Homeopathy (2008), Vol. 97(3), pp. 129-133(http://www.ncbi.nlm.nih.gov/pubmed/18657771)