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Syphilinum. (Luesinum.)

Syphilitic Virus. A Nosode.

Provings by Swan, Med. Adv., 1880, vol. 21, pp. 123-142.

Authorities quoted by Swan, Boardman, Wildes, Ballard, Eggert, Morgan, Ostrom, Bradshaw, Skinner, Theobald, Morrison, Clausen, Berridge, Burritt, Nichols, Jackson, Foster, Nash, Schmidt, Boyce, Hawley, Morrow, Haynes, Carr, Allen, H. C., Kent, etc.

The collection of cures and observations, by Thomas Wildes, Kingston, Jamaica published in the Homeopathic Physician, 1891, is incorporated.

The n signifies nosodes or symptoms from cases of disease.


- Chronic syphilitic headache affecting mind, Wildes, Hom. Phys, vol. 11, p. 272; Rheumatic ophthalmia, Berridge, Org., vol. 2, p. 461; Inflammation of cornea, Norton, Ophth. Therap., p. 180; Ozaena syphilitica, Wildes, Hom. Phys., vol. 11, p. 274; Ptosis, Wildes, Hom. Phys., vol. 11, p. 269; Cancer of right maxilla (relieved nightly pain), W. L. Reed, MSS., per Kent; Facial paralysis, Wildes, Hom. Phys., vol. 11, p. 269; Aphasia, Paralysis, Wildes, Hom. Phys., vol. 11, p. 269; Pain along spermatic cords, Boardman, Org., vol. 2, p. 448; Bubo, etc., Swan, MSS.; Leucorrhea, Berridge, Hom. Phys., vol. 3, p. 194; Asthma, Ostrom, Org., vol. 2, p. 262; Caries of spine, Nash, Hom. Phys., vol. 6, p. 15; Nervous chills, etc., Swan, MSS.; Rheumatism, Schmitt, Hom. Phys., vol. 4, p. 293; Papular eruption, Wildes, Hom. Phys., vol. 11; Blood-boil, Lepra-syphilis from vaccination, Wildes, Hom. Phys., vol. 11; Osteo-sarcoma in labia, Wildes, Hom. Phys., vol. 11; Syphilitic destruction of hard and soft palates, Wildes, Hom. Phys., vol. 11, p. 274; Syphilis, Skinner, Med. Inv., vol. 4, p. 568; Syphilitic neuralgia (worse at night), W. L. Reed, MSS., per Kent; Syphilitic prurigo and herpes, Wildes, Hom. Phys., vol. 11.

MIND. [1]

Loss of memory, n.
Loses remembrance of passing occurrences, names, dates, etc., while all occurrences previous to inception of disease are remembered as distinctly as ever. n.
Great difficulty, and sometimes impossibility of concentrating thoughts on particular subjects; yet at same time can recollect consecutive events and details which occurred twenty-five or thirty years previously, in order of occurrence, almost without effort. n.
Cannot remember names of persons, books or places.
Difficulty in making arithmetical calculations.
Very nervous, weeping without cause.
Cross, irritable, peevish. ~ Periodical neuralgia in head.
Very despondent, does not think will ever get better. ~ Syphilitic sore mouth.
Terrible dread of night, not on account of cough so much as on account of mental and physical exhaustion when she awakes; it is intolerable, death is preferable; she fears to prepare for night and is positively in abject fear of suffering, in form of exhaustion, on waking; it is agg. by cough, but it is quite independent of cough as she wakes in this awful state; always agg. as night approaches; leaves her about daylight, which she prays for. ~ Spring cough.
Feeling as if going insane, or about to be paralyzed.
A far-away feeling, with apathy and indifference to future.


Vertigo on looking up, seems to be caused by heat.


Headache: linear, from or near one eye backward; lateral; frontal; from temple to temple; deep into brain from vertex; as from pressure on vertex; in either temple, extending into or from eye, amel. by warmth; in bones of head; agg. by heat of sun; after sunstroke.
Sick-headache, pains intolerable, arteries of head full and pulsating violently; high fever, frequent retching on trying to vomit; menses regular, but very scanty.
Lancinating pain in occiput, invariably agg. at night. n.
Headache and great debility.
Neuralgic cephalalgia causing sleeplessness or delirium at night, always commencing about 4 P. M.; agg. at from 10 to 11, and ceasing at daylight.
Great loss of hair. n.
Nervous chills preceded by aching pains in head, especially in occiput and integuments thereof, head feeling heavy, sore, congested; also frontal headache about one-half or two-thirds inch wide across forehead under eyebrows; aching pains below waist, in pelvis and extremities, especially in tibia, which is sensitive to touch; pains commence about 4 P. M., culminate about midnight in delirium, and cease entirely at daylight.
Bursting sensation in vertex as from severe cold.
Pain from eyes through to occiput, with sensation of weight in occiput drawing head back, or as if it were pulled back; eyes ache and smart.
Constant linear headache, commencing at both angles of forehead and extending in parallel lines backward precursor of epileptic attack.
Heavy, crushing, cutting pain across base of cerebellum.
Heavy, clouded, dull feeling in base of brain.
Syphilitic cephalalgia in occiput, intolerable, extending to nervous ganglia of neck, causing hardening of cords; attacks at irregular intervals, especially after excitement. ~ Secondary syphilis.
Headache through temples, thence vertically, like an inverted letter T.
Coronal headache. ~ Secondary syphilis.
Headaches accompanied by great restlessness, sleeplessness and general nervous erethism.
Syphilitic headache for many months, piercing, pressing, excruciating over right eye, extending deep into brain; losing continuity of thought and memory; makes repeated mistakes in figures.


Suffusion and full feeling in face, throat and head, with innumerable small enlarged cervical glands.
Sore, one and a half inches in diameter, on occipital bone, covered with a thick, yellow-white scab.
Dirty eruption on scalp.


Red papulous eruption around left inner canthus, with isolated pimples on side of nose, cheek and eyebrow; these pimples were red, with depressed centre, circumscribed areola, became confluent where they were most dense; pimples bleed when scabs come off; agglutination of lids.
Myopia. n.
Sensation of heat with a little pain in outer half of left lids.
Sharp pulsating pain, occasionally at outer end of superior border of right orbit, apparently in periosteum.
Upper lids swollen.
During sleep lids adhere. ~ Infantile syphilis.
Ptosis: paralytica; eyes look sleepy from lowering of upper lid.
Diplopia, one image seen lower than other.
Strabismus paralytica, eye turning inward, and pupil can only be turned outward as far as median line.
Paralysis of superior oblique.
Chronic recurrent phlyctenular inflammation of cornea; successive crops of phlyctenules and abrasion of epithelial layer of cornea; intense photophobia; profuse lachrymation; redness and pain well marked; delicate scrofulous children, especially if any trace of hereditary syphilis remains.
Interstitial keratitis.
Chronic congested spots on eye, more often on temporal side, usually about one to three lines behind cornea, of a dark-red color, apparently embedded in sclera. ~ Syphilis.
Photophobia, black spots, shreds or veils before sight.
Itching of left inner canthus.
Left eyeball covered with funguslike growth, pain intense, agg. at night.
Eyes red and inflamed.
Acute ophthalmia neonatorum. n.
Eyes swollen and closed with syphilitic ophthalmia, pus running out of them. ~ Infantile syphilis.
Redness and swelling of outer half of both lower tarsal edges.
Acute left conjunctivitis, with considerable pain in eyeball, photophobia and lachrymation, followed by iritis; nocturnal aching in eyeball, pain extremely violent from 2 to 5 A. M.; sight impaired. ~ After syphilis three or four years ago.
Syphilitic iritis, intense pain steadily increasing night after night; agg. between 2 and 5 A. M., coming almost to the minute and ceasing same way. ~ Secondary syphilis.
Iritis with photophobia, congestion of conjunctiva and sclerotica, with puffiness of conjunctival mucous membrane; chemosis, pupil immovable, diminution of sight; supraorbital pain.
Pain in right inner canthus as if blood went there and could go no further, also in right temple. ~ Rheumatic iritis.
At 1 P. M. scalding lachrymation of right eye with shooting therein, followed by shooting from around eye into eye; eye red and closed; this lasted about an hour, then decreased, ceasing about 3 P. M.; recurred for two successive days and again four days afterward in a slighter degree, but at same hour. ~ Rheumatic iritis.
On turning eye to left feels momentary coldness in inner half of right eye. ~ Rheumatic iritis.
On waking, gum in right canthus. ~ Rheumatic iritis.
On walking across room, right eye sensitive to air, aches on using it. ~ Rheumatic iritis.
Both eyes glued in morning; conjunctiva injected; photophobia, constantly wears a shade. ~ Ozaena.
Eyes dull. ~ Infantile syphilis.
Ophthalmic pains, agg. at night, amel. by cold water.
Right eye alone affected, congestion of conjunctiva and sclerotica, with some chemosis; lids inflamed, especially at outer canthus; sensation of sand in eyes; lids agglutinated in morning; great photophobia. ~ Hereditary syphilis.
Left eye closed, upper lid swollen as large as half an English walnut; deep red, not much pain, with oozing of purulent matter from between lids.
Neuralgia every night, beginning about 8 or 9 P. M., gradually increasing in severity until it reached its height about 3 or 4 A. M., and after continuing thus for two or three hours gradually decreased and finally ceased about 10 A. M.; attacks gradually get more severe and last longer; first feels cold all over, almost a shiver; then soreness as if beaten in right half of head, extending a little beyond middle line on vertex; in about thirty minutes scalding lachrymation from right eye, with shooting backward increasing to a boring backward therein; eye is very red and closes, with photophobia; gnawing pains extend down right side of face and whole of nose; head is worst when eye is bad; during paroxysm right eye feels as if lids were open wide, and cold air blowing on exposed eye; she perceives a horizontal band across pupil of right eye hindering sight; this came on soon after paroxysms commenced; eye amel. by placing handkerchief on head and letting it hang over eyes, also by gentle pressure, though she cannot bear much pressure; it is more painful when lying on right (affected) side when also right side of head feels sore; right eye red, and red vessels run all over it, converging toward iris; right pupil horizontally oval; right iris looks dull and there is a slight brown hue around pupil; left eye normal; attacks seem to have originated from sitting at a window in a cold draft, right eye being next window. ~ Rheumatic ophthalmia.


Intense earache in right ear, incisive pains thrusting into ear; purulent, watery discharge from ear with pain.
Gathering in left ear which discharges a great quantity of pus. ~ Hereditary syphilis in a child.
Deafness gradually increasing until she could scarcely hear at all.
Complete deafness; nothing abnormal to be seen.
Catarrhal or nerve deafness with marked cachexia.
Calcareous deposit on tympanum.
Small, acrid, watery discharge occasionally from ears, no deafness. ~ Ozaena.


Left side of nose, inside ala, itching.
Nose stuffed up and burning.
Attacks of fluent coryza.
Offensive, thick yellow-green nasal discharge; during sleep dry scabs form in both nostrils; following an application of salve for sore eyes; left submaxillary gland, which had been swollen and indurated, softens, discharges and, after forty-five days; begins to heal slowly.
Ozaena syphilitica; Syph. brought out an eruption of sores with a fiery-red base on nose and over frontal sinuses.
Left side of nose inside and out very sore, likewise lips and chin; sores itching and scabbing over. ~ Hereditary syphilis.
Itching in nostrils.


Face drawn to one side, difficulty of speaking, masticating, blowing. n.
Spasmodic twitching of many muscles, especially in face (paralysis agitans), with great melancholy and depression of spirits.
Facial paralysis right side, thick speech, hemicrania, jactitation of right eye and lid.
An old gentleman has had, for some years, cancer on right malar bone; no rest, his agonies excruciating in extreme (relieved).
Face pale. ~ Curvature and caries of cervical spine.
Itching, scabby, eczematous eruptions singly or in clusters, looking like herpes.
Nose and cheeks covered with eruptions and scabs; scabs in layers rising to a point.
Dark purple lines between alae nasi and cheeks.
A boy, aet. 20 months, fretful, peevish, cross and crying, tossing in his sleep, grinding his teeth, face dotted with papules filled with a watery yellowish matter, most on edges of lids; teeth irregular, arms and legs emaciated, very tottery on his feet, very nervous.


Lips and teeth covered with bloody mucus. ~ Infantile syphilis.
Sores on lips and chin, especially left side scabbing over.


Single small lunae cleft in upper incisors, permanent set, which incisors are dwarfed in their general dimensions, and converge at their tips; inherited syphilis. n.
First central upper incisors serrated, permanent teeth point toward each other, inner side concave, edges serrated. n.
Children's teeth are cupped.
Teeth decaying at edge of gum and breaking off. n.
Pain in right upper jaw, as if from teeth, with swelling of face.
Painless fluttering occasionally in teeth, very peculiar, as of something alive, cannot detect which tooth it is.
Felt like a worm in tooth, could not tell which tooth.
Singular feeling as if teeth had all got out of place, and on closing jaws teeth do not come well together.
Occasional aching in left upper teeth.


Tongue red and thick; two deep cracks running length wise in it; one on each side of median line.
Aphasia; facial paralysis left side; ptosis and sudden paralysis of left optic nerve, causing many weeks of blindness; partial paralysis of tongue, which also protruded, crooked; sluggish heaviness of speech, complete hemiplegia for first thirty-six hours, afterward partial for several weeks.
Aphasia, difficulty of finding words; debility.


Fetid breath. ~ Secondary syphilis.
Tongue coated; white, edges indented by teeth.
Tongue turns to one side when protruded; difficulty in mastication, cannot turn food with tongue so readily from right to left, as in other direction. n.
Putrid taste in mouth before epileptic fit.
Tongue very red and thick; covered with herpetic eruption, two deep cracks running lengthwise on each side of median line, making it difficult to swallow. ~ Secondary syphilis.
Tongue thickly coated, dirty, edges indented or serrated by teeth. n.
Twenty ulcers in mouth, every part of which was involved, on top and under side of tongue, on lips, in buccal cavity, fauces and in nose; two large ones, one on each side near apex of tongue, very much swollen, one on right side had a gangrenous centre, rest lardaceous bottoms with bright, fiery-red edges, and were cut down as with a knife, felt hard like an indurated chancre; septum of nose threatened, both alae nasi very painful, smarting with burning as if on fire; pains and burning prevented sleep; hungry but could eat nothing but fluids as mastication was impossible; tongue heavily coated white, large quantities of stringy viscid saliva running from mouth, of a sweetish taste; a putrid sickening odor filled whole house; all symptoms agg. toward night. ~ Secondary syphilis.
Herpetic eruption in mouth, tonsils, hard palate and fauces, completely covering inside of mouth and throat, making it very difficult to swallow even liquids. ~ Secondary syphilis.
Syphilitic destruction of hard and soft palates.


Chronic hypertrophy of tonsils. ~ Hereditary syphilis.
Chancrous ulcer extending across velum palati to left pillar of pharynx. ~ Secondary syphilis.
Acute pharyngitis. ~ Secondary syphilis.


Appetite indifferent and capricious. ~ Psoas abscess.
Total loss of appetite for months, little or nothing satisfies him; formerly was generally ravenous. ~ Caries of dorsal vertebrae.
Loss of appetite. ~ Rheumatism.
Tendency to heavy drinking; alcoholism.
Aversion to meat.
Dyspepsia; flatulence, belching of wind; nervous dyspepsia.


Heartburn with pain and rawness from stomach to throat pit, often with cough.
Vomiting for weeks or months due to erosion from superficial ulceration of lining of viscus, herpetic, of syphilitic origin.


Pain or distress deep in abdomen as if in omentum.
Feeling of heat internally in hypogastric region.
Pains in right groin followed by swelling of glands.
Large painless bubo in right groin opened and discharged freely. ~ Secondary syphilis.
Slight lancinating pains in one groin, agg. at night.
Inguinal bubo.


Bowels torpid for five weeks. ~ Periodical neuralgia in head.
Obstinate constipation for many years; rectum seemed tied up with strictures; when injections were given agony of passage was like child-bearing.
Chronic constipation, with fetid breath, earthy complexion, gaunt appearance.
Stools very dark and offensive. ~ Infantile syphilis.
Stools too light-colored. ~ Rheumatism.
Bilious diarrhea at seashore, painless, driving her out of bed about 5 A. M.; stools during day, later causing excoriation; face red, suffers from heat; occasional painless, whitish diarrhea when at home, always amel. by going to mountains.
Obstinate cases of cholera infantum.
Lower portion of rectum hanging out like a ruffle, looking like a full-blown rose fully three inches in diameter, and sensitive; constant weak dragging sensation in rectum, extending as far as sacrum.
Fissures in anus and rectum.
Two indurated ulcers at mouth of anus somewhat sore; slight itching of moist anus. ~ Primary syphilis.


Itching in orifice of urethra.
(In sick:) A sensation, in morning on going to urinate, as if male urethra were stuffed up, or clogged, about an inch from orifice.
Scalding urine.
Urination difficult and very slow; no pain, but a want of power, so that he has to strain. ~ Secondary syphilis.
Urine infrequent, not oftener than once in twenty-four hours, scanty, of a golden-yellow color.
Profuse urination after chill; passed during night nearly a chamberful.
Rich lemon yellow scanty urine.
Frequent urging to urinate all night, at least from 5 to 7 P. M. until 5 A. M.


Chancre on prepuce.
Burning in chancre size of a split pea, on prepuce above corona glandis; edges red and raised, bottom covered with lardaceous deposit; glans purple, on left side covered by an exudation.
Chancre on penis, third in two years, all on same spot. ~ Secondary syphilis.
Aching of genitals, could not sit still for over a month.
After suppressed chancre, disease attacked testes and scrotum, which became painful and swollen; this was supposed to be cured, but ever since, every few weeks, if exposed at all to damp weather, would be seized with pains as if in kidneys, seemingly traversing ureters, but instead of passing into bladder followed spermatic cord, down groins and into testes; pain agonizing, chiefly in cord, in present attack in right; pricking in chancre.
Constant pain in anterior part of right thigh, agg. while standing, painful all night, preventing sleep; bubo in left inguinal region size of a pigeon's egg, purple, fluctuating; night sweats.
Chancroid, phagedenic, spreading rapidly; buboes commencing in each groin.
Inflammation and induration of spermatic cord.


Uterus and all surrounding parts loose, soft and flabby; profuse, thick, yellow leucorrhea; constant pain across small of back.
Slight whitish leucorrhea.
Yellow offensive leucorrhea, watery or not, so profuse it daily soaks through napkins and runs to heels of stockings if much on her feet.
Profuse yellow leucorrhea, agg. at night; in sickly, nervous children. ~ Inherited syphilis.
Soreness of genitals, and muco-purulent discharge, in a child.
Acrid discharge causing violent itching and inflammation of external organs, agg. at night from warmth of bed, parts very tender; itching and inflammation amel. during menses.
Nocturnal aggravation of right ovarian pain, preventing sleep.
Sore on right labium majora, extending to left. ~ Secondary syphilis.
Intense itching of vulva on rising in morning, continuing until 10 o'clock.
Menses painful, two weeks too soon; pink-red, bright, profuse, running free for some days; napkins wash easily.
Painful menses.
Sensitiveness of os uteri, increasing to intolerable pain at menses, or on introduction of fingers or penis; frequently causes abortion. n.
Sharp zigzag shooting pains in region of uterus.
Ovaries congested and inflamed; tendency to ovarian tumors.
Sore aching in left ovarian region, extending to right with darting pains.
Left ovary swollen, during coitus, at moment of orgasm, a sharp cutting pain like a knife, and twice there was smarting as of a sore; ovary swelled so much that its size and shape could easily be felt through abdominal walls (caused by Buboin).
Uterine and ovarian diseases with pronounced nervous disorders, especially in married women.
Mamma sensitive to touch, feeling sore; during menses, and at other times.


Hoarse, almost complete aphonia, day before menses.
Diseased cartilages of larynx. ~ Tertiary syphilis.


Chronic asthma; in Summer, especially when weather was warm and damp; most frequently in evening, passing off at daybreak; soreness of chest, with great anguish and inability to retain a recumbent position; in Winter, severe bronchial cough succeeded asthmatic attacks; a regular type of chills and fever developed; suffered from this many years before.
Oppression of chest to such an extent as almost to arrest breathing; asthma caused by sensation as if sternum were being gradually drawn toward dorsal vertebrae; expansion of chest difficult; confusion of mind, as if unconsciousness might follow.
Lack of sleep produces a sudden faintness and sinking sensation in chest; three spells succeeded each other during a single night.
Attacks of spasmodic bronchial asthma for twenty-five years; they come on only at night after lying down or during a thunderstorm, producing most intense nervous insomnia, entirely preventing sleep for days and nights.
Violent attacks of dyspnea, wheezing and rattling of mucus, from 1 to 4 A. M.

COUGH. [27]

Hard cough, agg. at night, when it is continuous, preventing sleep.
Hard, constant cough, with thick, yellow, tasteless expectoration.
Dry, racking cough, with thick, purulent expectoration, caused by a sensation of rasping or scraping in throat, always agg. at night. ~ Secondary syphilis.
Whooping cough, with terrible vomiting.
Dry, sharp, hacking cough without expectoration, but with rawness, scraping and burning from fauces to stomach pit; with a whoop in inspiration and a choking sensation from fauces to bifurcation of bronchia, great mental distress.
Cannot lie on right side, as it causes a dry cough.
Cough and dyspnea come on after midday dinner, has to fight for breath, feels as if she would be suffocated; symptoms last all night, amel. at daybreak (improved).
Expectoration of white phlegm.
Muco-purulent expectoration, greyish, greenish, greenish-yellow, tasteless.
Expectoration without cough, quite clear white, feels like a round ball and rushes into mouth. ~ Nervous asthma.


Pain and oppression at bifurcation of bronchia and in larynx, it hurts her to breathe.
Rattling in chest and throat. ~ Infantile syphilis.
Pain in centre of chest as if skin were drawn up, on drawing head back.
Sensation of pressure under upper part of sternum.
Pain and pressure behind sternum.
Angina; ptosis left eye; facial paralysis left side, slight aphasia; impotence (relieved).


Lancinating pains in heart, at night, from base to apex (Medorrhinum has reverse).
Valvular disease of heart.


Eczematous herpetic eruptions.


Heavy aching and stiffness from base of neck up through muscles and cords into brain.
Great pain in back in region of kidneys, agg. after urinating. ~ Secondary syphilis.
Pain in coccyx at its junction with sacrum, sometimes in lower sacral vertebrae; agg. on sitting, with a sensation as if swollen, though it is not.
Pains commencing in sacral regions internally, and apparently coming around to uterus.
Caries of cervical spine with very great curvature in same region, directly forward, occiput sinking down to a level with it and resting on protuberance of curvature; often nearly a teaspoonful of calcareous matter would be discharged at a time, and on evaporating it a quantity of dry powder, looking like phosphate of lime, would be left; pain in curvature always agg. at night (no proof of syphilis).
Rigidity of muscles.
A heavy, dragging, dull feeling in lumbar region, with stiffness and want of elasticity.
Caries of dorsal vertebrae with acute curvature, numerous cloacae communicating with diseased bone, one much larger than rest, exuding a sanious, offensive pus, and surrounded with proud flesh; great thickening and induration of surrounding parts from effusion of lymph; percussion or pressure not endurable; two abscesses in groins, left having been opened a year before, right about a month ago; least motion gave him great pain by day, and terrific pain by night; for five months, every night most intense neuralgic pains, commencing generally from 5 to 7 P. M. and never terminating till about daylight or about 5 A. M.; pains in muscles of loins, generally in left, sharp, cutting spasms, terrible to bear, preventing sleep and forcing him to cry out; agg. by least motion, and slightly amel. by warm poultices.
Psoas abscess first left then right, latter discharged more than a quart of offensive greenish pus when opened; severe nocturnal pains, affecting upper sacral, lower dorsal and left cervico-facial regions, steadily increasing; they occurred twice, each time twenty-one days after either psoas abscess had been opened.
Enlargement of cervical glands and a number of pedunculated pin-head warts on neck; cured by Syco-syphilinum. ~ Hereditary syphilis; girl aet. 10.
Enlargement of glands in different parts of body, particularly abundant about neck; indurated and slightly painful, causing a sensation of uncomfortable fullness and suffusion in face, throat and head. n.
Nocturnal aggravation of pains in back, hips and thighs.
Enormous swelling of glands of head and neck. ~ Hodgkin's disease.


Rheumatism of shoulder joint or at insertion of deltoid, agg. from raising arm laterally.
Can only raise arms to a right angle with axilla; trying to force them higher causes muscles to suddenly become paralyzed and they drop pendant. n.
Lameness and pain of arm on motion, particularly on raising arm up in front as if reaching; pain located about insertion of deltoid in upper third of humerus, not painful to pressure.
Fingers and thumbs have runarounds. ~ Infantile syphilis.
Hands badly ulcerated on backs. ~ Secondary syphilis.
Right second finger swollen and stiffened. ~ Secondary syphilis.


Swelling of legs from knees down, soles painful when standing on them; swelling goes down in morning, comes back at night.
Pains in lower extremities, excruciating, completely banish sleep; agg. from hot fomentations; amel. pouring cold water on them. n.
Cannot sit in a low chair, or squat down, owing to loss of control over knee and hip joints. n.
Pains in long bones of lower extremities, also in joints. n.
Dull pain over backs of feet to toes, began soon after getting into bed, lasting until 4 or 5 A. M.
For two or three winters intense cold pain in both legs, agg. in left, came on every night on lying down, lasting all night; amel. by getting up and walking, and in warm weather.
Pain in three toes of right foot as if disjointed.
Slight contraction of tendons beneath right knee. ~ Psoas abscess.
Tearing pains in hip and thighs, agg. at night, amel. about daybreak, amel. by walking, not affected by weather (improved).
Sharp rheumatic pain, burning like fire, in left side of right instep and below inner malleolus, prevents her from moving foot, amel. when toe is pointed inward; agg. in evening, continuing during night, waking her up suddenly every two or three hours, worst from 1.30 to 3.30 A. M., amel. toward daybreak (improved).
Redness and rawness with terrible itching between toes. ~ Secondary syphilis.
Bone pains in knees and feet. ~ Secondary syphilis.
Bubo with pain in spot on middle of right thigh in front, only when standing and on deep pressure, which seemed to touch spot, which was apparently on periosteum.
Two ulcers larger than a crown piece, dirty, stinking, sloughing, with jagged, elevated edges, one on thigh above patella, another on head of tibia; two large pieces of bone came away from head of tibia. ~ Secondary syphilis.
Osteosarcoma in centre of right tibia the size of half an ostrich egg, pains agonizing at night, growth irregular, spongy, partly laminated, very hard. ~ Secondary syphilis.
Severe attacks of aching in lower limbs. ~ Secondary syphilis.
Contracted painful feeling in soles of feet, as if tendons were too short.


Aching pains in limbs like growing pains.
Gradual rigidity of all joints after eruption; flexors seem contracted.
Rheumatic swelling of left wrist and big toe, bluish-red, with pains as if somebody sawed at his bones with a dull saw; amel. by heat of stove; agg. from sundown to sunrise; no appetite; has lasted two weeks. ~ Rheumatism.
Feeling of numbness in palms and soles, at times a prickly sensation as if numb parts were punctured by a great number of needles.
Excruciating arthritis; swelling, heat and redness intense.
Rheumatism, muscles are caked in hard knots or lumps.


No position suits him. ~ Syphilitic neuralgia.
Standing: pain in thigh; soles painful; pain in thigh agg.
Sitting: pain in coccyx agg.; or squatting, can not on account of loss of control over knee and hip joints; on stool amel. pain in head.
Recumbent position: impossible with asthma.
Lying: on right side causes cough; sore throat agg.
Motion: pain in groins agg.; raising arm pain in deltoid agg.; pain in instep agg.; slow, amel. tearing pain through body.
On drawing back head: pain in chest as if skin were drawn up; pain in neck amel.
Pointing toe inward: pain in instep amel.
Walking: pain in hip and thighs amel.

NERVES. [36]

Utter prostration and debility in morning.
Epileptic convulsions after menses.
Body, extremities and face covered with syphilides; a sticking soreness begins in throat every evening between 6 and 7 o'clock and continues to grow agg. during night; exceedingly restless until 4 A. M.; then a restless sleep for a few hours; can scarcely swallow; when swallowing a sensation as of throat tearing to pieces; continual throbbing in throat, agg. from cold and hot drinks, and agg. lying down; throbbing in temples and ears, boring in ears meeting in centre of brain; sensation as if top of head were coming off; drawing pain in eyes agg. from lamplight; teeth pain when eating, also when taking anything hot or cold, feel as if they were loose, amel. pressing teeth together and pressing throat with hands; excessive flow of saliva, it runs out of mouth when sleeping; severe pain in neck; bending back head, amel. pain in neck; aching pain in shoulders and knees; rending tearing pains throughout body, amel. moving about slowly; had his wife hide his revolver lest in a fit of desperation he might kill himself, as was his desire during extreme paroxysms of pain; strikes wall with fist and beats head against wall for relief; stools hard, dry like sheep dung; desire for stool three or four times a day, but only a little scentless wind passes which gives relief; sitting on stool amel. pain in head; is easily offended, gets desperate, cannot bear to be alone, great anxiety about getting well; at night no position suits him, walks floor or goes into street and moves about slowly; sleepy all time but cannot sleep; dreams about his disease; amel. in open air; frequent urination with sudden desire; discharges large quantities of muddy urine. ~ Syphilitic neuralgia.

SLEEP. [37]

Great restlessness at night, impossibility to keep long in one position. n.
Absolute sleeplessness (vies with Sulphur in producing quiet, refreshing sleep).
Wakes soon after midnight and cannot sleep again until 6 A. M.

TIME. [38]

After midnight: weary, tired pains.
From 1.30 to 3.30 A. M.: pain in instep agg.
Midnight until 6 A. M.: cannot sleep.
Morning: lids agglutinated; urethra as if clogged; until 10 itching of vulva; prostration.
At 1 to 4 A. M.: attacks of dyspnea.
At 5 A. M.: diarrhea drives her out of bed.
From 11 to 1 P. M.: fever.
After midday dinner: cough and dyspnea.
At 2 P. M.: pains begin, reach acme 9 P. M., continue until daybreak.
From 1 to 3 P. M.: rheumatic iritis agg.
At 4 P. M.: headache begins.
From 2 to 5 A. M.: aching in eyeball agg.
From 6 to 7 P. M.: sticking soreness in throat begins.
At 8 or 9 P. M.: neuralgia begins.
Night: headache agg.; lancinating in occiput agg.; delirium; neuralgic cephalalgia agg.; pain in fungous growth of eyeball agg.; ophthalmic pains agg.; pains in groin; profuse urination; frequent urging to urinate; pain in thigh agg.; acrid leucorrhea agg.; ovarian pain agg.; asthma agg.; cough agg.; cardiac pain; pain in spinal curvature agg.; pain in back, hips and thighs agg.; swelling of legs; pains in feet agg.; pain in tibia; restlessness; rheumatic pains agg.; biting sensation.


Warmth: amel. headache; of bed, syphilitic eruption agg.
Heat of sun: agg. headache.
Heat of stove: amel. pain in swollen wrist and big toe.
Hot or cold things: toothache agg.
Hot fomentations: pains in legs agg.
Cold draft: rheumatic ophthalmia.
Cold water: ophthalmic pains; pains in lower extremities agg.
Damp weather: pains across kidneys into spermatic cord and testes; pains in muscles.
Warm and damp weather: asthma agg.
At seashore: bilious diarrhea.
Air: eye sensitive to; syphilitic neuralgia.
In mountains: bilious diarrhea amel.
During thunderstorm: bronchial asthma agg.

FEVER. [40]

Great pain in head, whole body extremely cold, looked blue; wanted to be covered with blankets, yet could not get warm, no appetite; sleeping almost all time, could scarcely be aroused. ~ Secondary syphilis.
Nervous chills preceded by aching pains in head, especially occiput and in scalp over that part of head; pains below waist, in pelvis, in legs, especially in tibia, which is sensitive to touch; head feels heavy and sore, as if congested; bowels torpid for five weeks; cross, irritable, peevish; pains commence every day about 4 P. M., culminating at midnight with delirium, and disappear at daylight.
After retiring, nervous chill commencing in anus and running down legs with spasmodic sensation; followed by distress in bowels and immediate desire for stool; passed a little urine when chill and desire for stool ceased; afterward profuse urination, eructations amel. chill.
Dry, hot fever shortly after going to bed, with dry, parched lips and great thirst; during fever intensely hot, wants to throw off covering, puts feet out of bed and against wall to cool them; high fever in middle of day, heat being intense, with sensation as if burning up; thirst for large quantities often, sensation of burning internal heat very marked; fever preceded by slight chill and followed by sweat and great debility.
Fever from 11 to 1 P. M. daily; perspires when she begins to get over fever; pain in back, agg. between shoulders, no ambition or desire to move.
Profuse night sweats, sleepless and restless.
Excessive general debility and continued night sweats, latter being most marked between scapulae and down to waist. n.


Gradually increasing: nightly neuralgia; deafness.
Gradually increase and decrease: pains in muscles.
Three or four times a day: desire for stool.
Three spells in one night: faintness and sinking in chest.
Every night: neuralgia, 8 or 9 P. M.
For days and nights: nervous insomnia with asthma.
Lasting a week or two: rheumatic neuralgic pains in muscles.
Two weeks: rheumatic swelling of wrist and big toe.
For five weeks: bowels torpid.
For many weeks: blindness.
For months: total loss of appetite.
For many months: syphilitic headache.
For many years: constipation.
For twenty-five years: bronchial asthma.
Spring: cough.
Summer: chronic asthma.
Winter: bronchial cough succeeding asthma in Summer; cold pain in legs.


Left: eruption about inner canthus; heat and pain in outer half of lids; itching of inner canthus; fungous growth on eyeball; conjunctivitis, eye closed; gathering in ear; itching in nostril; abscess in submaxillary gland; nose sore inside and out; sores on lips and chin; aching in upper teeth; facial paralysis; ptosis and paralysis of optic nerve; chancrous ulcer from velum palati to pillar of pharynx; exudation on glans penis; bubo; swollen ovary painful during coitus; swelling of wrist and big toe.
Right: headache over eye; pulsating pain at outer end of superior border of orbit; pain in inner canthus; gum in canthus on waking; eye sensitive to air; conjunctiva and sclerotica congested; perceives a horizontal band across pupils; iris looks dull; head as if beaten; scalding lachrymation; gnawing in face and nose; eye feels as if lids were open and air blowing on it; earache; facial paralysis; jactitation of eye and lid; pain in cancer on malar bone; pain in upper jaw; pain and swelling in groin; painless bubo opens and discharges; pain in anterior thigh; second finger swollen and stiff; pain in toes as if disjointed; contraction of tendons beneath knee; pain in instep.
From left to right: pain in ovaries; psoas abscess.
From right to left: cannot turn food readily with tongue; sore on labia majora.
On turning eye to left: coldness in under half of right eye.
Linear pain: from or near eye backward.


A seething feeling as of hot water or hot oil running through all veins of the body, all night long; as if going insane or about to be paralyzed; a far-away feeling, with apathy; as if head were pulled back by weight; as if blood went to right inner canthus and temple and could get no farther; as of sand in eyes; as if right eye were open wide and cold air blowing on it; fluttering as of something alive in teeth; as of a worm in tooth; as if teeth had gotten out of place; distress as if in omentum; as if rectum were tied up with strictures; as if urethra were stuffed up or clogged; as if sternum were being drawn toward dorsal vertebrae; as if she would suffocate with cough; as if skin were drawn up in centre of chest on drawing head back; coccyx as if swollen; as if toes of right foot were disjointed; like growing pains in limbs; as if bones were sawed; palms and soles as if punctured by needles; as of throat tearing to pieces; as if top of head were coming off; as if teeth were loose; as of a nervous chill commencing in anus and running down legs; as if bitten by bugs.
Pain: in eyeball; in right upper jaw; deep in abdomen; in right groin; across small of back; in larynx and bifurcation of bronchia; in region of kidneys; in sacrum; in coccyx; in long bones of legs; in joints; in periosteum and bones.
Excruciating pain: over right eye; in cancer on right malar bone; in spermatic cord; in lower extremities; in joints, with arthritis.
Lancinating: in occiput; in groin; in heart.
Cutting: across base of cerebellum; in left ovary during coitus; in muscles of loins.
Bursting: in vertex.
Tearing: in hip and thighs; throughout body.
Gnawing: in right side of face and in nose.
Crushing: across base of cerebellum.
Piercing: over right eye.
Shooting: in right eye; from around eye into eye; in region of uterus.
Incisive thrusting pain: in right ear.
Boring: in right eye; in ears.
Sticking soreness: in throat.
Pricking: in chancre; in palms and soles.
Darting: in ovarian region.
Neuralgic pains: in right side of head, face and eye.
Rheumatic pain: in shoulder joint and insertion of deltoid; in right instep and below inner malleolus.
Burning: in nose; in ulcers in mouth; in chancre; from fauces to stomach pit; in right instep and below inner malleolus.
Aching: in pelvis and extremities; in tibia; in eyes; in eyeball; in teeth; in genitals; from base of neck to brain; in lower limbs; in shoulders and knees.
Sore aching: in ovarian region.
Soreness: in head; as if beaten in right half of head; in nose; in mamma; of chest; in soles.
Smarting: in eyes; in ulcers in mouth.
Biting: in skin in different parts of body.
Rawness: from fauces to stomach pit.
Choking: from fauces to bifurcation of bronchia.
Scraping: from fauces to stomach pit.
Dragging: in rectum; in lumbar region.
Drawing pain: in eyes.
Pulsating pain: at outer end of superior border of right orbit.
Throbbing: in temple and ears; in throat.
Pressing: over right eye; under sternum.
Dull pain: over backs of feet to toes.
Tired pain: in limbs.
Cold pain: in legs.
Contraction: in soles of feet.
Stiffness: in lumbar region.
Numbness: in palms and soles.
Full feeling: in face, throat and head.
Heaviness: in head; in base of brain; in lumbar region.
Weight: in occiput.
Sinking sensation: in chest.
Heat: in outer half of left eyelids; in hypogastric region.
Coldness: in inner half of right eye.
Itching: in left inner canthus; inside of nostrils; of anus; in orifice of urethra; of female genitals; between toes.


Shifting pains of a rheumatic character obliging a repeated change of position and posture. n.
Pains commence at 2 P. M., gradually increase until they reach their acme at 9 P. M., continuing exceedingly acute until 3 or 4 A. M.; subsiding with daybreak.
Pain more particularly agg. in, or confined to, muscles and joints of lower limbs, for four or five weeks, then they seemed to go to periosteum and bone itself, becoming deeper and more profound. n.
Pains produce two sensations, an external one which seems to lie in muscles and joints and an internal one which is deeper and much more unbearable, so much so that it seems by its profound nature to control external ones and to cause them to disappear, afterward reappearing intensified in external sensation. n.
Pains in limbs every night after midnight, weary, tired pains, making rest impossible, could lie nowhere without suffering in part on which he rested; agg. in lower limbs; much perspiration which partly relieved. ~ Rheumatic fever.
Rheumatic neuralgic pains in all muscles, even in cremaster, not in joints; darting pains in irregular attacks, sometimes lasting a week or two; pains gradually increase and decrease; agg. in damp and especially in frosty weather; agg. at 4 or 5 P. M., attain their height at 2 or 3 A. M., ceasing about 8 A. M. (improved).
Rheumatism with sweating of hands, wrists and legs below knees and feet, with great soreness of soles, agg. at night.
Extreme emaciation. ~ Psoas abscess. ~ Infantile syphilis. ~ Caries and curvature of cervical vertebrae.
Though 17, looked 12, was so reduced and dwarfed; great attenuation of soft parts throughout, spare and hollow; confined to couch for about three years and for one year scarcely off his back; after disappearance of pustular eruption a gradual rigidity of all joints ensues and all flexors seem to become contracted and shortened; this causes inability to close fingers on a fork, knife or spoon, and a partial inability to lift foot in order to step up stairs, except with great difficulty, by using a cane and only a step up or down at a time.
Peculiar disagreeable odor from body.
Adenitis, leaving almond-shaped kernels of varying sizes abundant about neck.


Touch: tibia sensitive; os uteri sensitive.
Pressure: pain in spot on middle of right thigh in front agg.; of teeth together amel. pain; throat better.
Sunstroke: headache.

SKIN. [46]

Pustular eruption on different parts of body; in patches on certain places, particularly on wrists and shins, where bones are nearest cuticle, and isolated other large pustules on other parts, these break, discharging an ichorous fluid for one or two days, then heal, leaving characteristic pockmark cicatrice; patches take longer to heal, discharging same fluid till healing process commences.
After healing of chancre a fresh pustular eruption appears on different parts of body, which, when pustules have discharged an ichorous liquid and healed up, leaves fresh, coppery pockmarks; Medorrhinum removed it permanently causing it to turn yellow-brown, dry at edges and scale off, leaving skin permanently clear and free.
Biting sensation in different parts of body, as if bitten by bugs, at night only.
Syphilitic rash, very prominent on forehead, chin, arms and front of thorax, an abundance of fine scales peeling off; large prominent spot on centre of forehead, filled with fluid, as also are some smaller patches. ~ Secondary syphilis.
Syphilitic bullae discharging freely on cheeks, under chin, on back of shoulders, on scalp and other parts of body. ~ Infantile syphilis.
Maculae over back, chest, abdomen, arms and legs, but not on any uncovered part of body. ~ Secondary syphilis.
Several elevated spots on arm, stomach, leg and finger; has them habitually on face, chiefly on left cheek.
A blood-boil on arm; face broken out with a lumpy fiery rash.
Eruption over whole body not elevated, but could be distinctly felt by passing hand over skin; after Syphilinum 1m eruption came rapidly to surface; at same time a disagreeable odor began to be developed; eruption reddish-brown like smallpox pustules, without central depression; body covered with it, except scrotum and penis; increased, completely covering inside of mouth and throat, making it difficult to swallow even liquids; eyes also covered, making him completely blind; intolerable smell from body; tips of pimples became filled with pus; agg. from warmth of bed; fetid breath; eruption developed still more, a great quantity of pus, with intolerable itching, yet could not scratch as it was extremely sore; eruption left skin of entire body covered with dull, reddish, copper-colored spots, which in cold looked blue. ~ Secondary syphilis.
Copper-colored maculae from crown of head to sole of foot. ~ Secondary syphilis.
Pemphigus looks like a pock, often confluent, and persistently reappears.
Skin is bluish.


A boy, aet. 20 months; papular eruption.
A boy, aet. 4 1/2; syphilitic prurigo and herpes.
A boy, aet. 10; destruction of tissue in hard and soft palates.
Girl, aet. 10; enlarged cervical glands, and warts in neck (Syco-syphilinum); hereditary syphilis.
Though 17, looked 12, emaciated; syphilitic eruption; affection of joints.
A young lady, blood-boil on arm, lepra-syphilis after vaccination.
A woman, aet. 29, delicate from a child; ozaena syphilitica.
A woman, aet. 40; facial paralysis.
Man, aet. 48, robust, weight 250 lbs., height 5 feet 9 inches; rheumatism.
A man, syphilitic; osteosarcoma on tibia.
A bookkeeper, chronic syphilitis; headache.
A man; aphasia with hemiplegia.
Mrs. —, suffering from diabetes mellitus, subject to rheumatism in rainy weather; rheumatic ophthalmia.
Mr. Y., nocturnal syphilitic neuralgia.
A man, aet. 60; syphilitic destruction of hard and soft palates.
A man, aet. 76; aphasia and debility.


Compare: Aurum, Mercur., Kali jod. and other anti-syphilitics.


Source: The Guiding Symptoms of Our Materia Medica Vol. 10, 1891
Description: Clinical materia medica of Syphilinum
Remedies: Syphilinum
Author: Hering, C.; Raue, C.G.; Knerr, C.B.; Mohr, C.
year: 1891
Editing: errors only; interlinks; formatting
Attribution: Legatum Homeopathicum
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